Both Rb and E7 are regulated by the ubiquitin proteasome pathway in HPV-containing cervical tumor cells.
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Host-pathogen interactome mapping for HTLV-1 and -2 retrovirusesUSP11 stabilizes HPV-16E7 and further modulates the E7 biological activityThe global transcriptional effects of the human papillomavirus E6 protein in cervical carcinoma cell lines are mediated by the E6AP ubiquitin ligase.Epstein-Barr virus latent antigen 3C can mediate the degradation of the retinoblastoma protein through an SCF cellular ubiquitin ligaseHuman Papillomavirus: Current and Future RNAi Therapeutic Strategies for Cervical CancerGene Expression Analysis of the 26S Proteasome Subunit PSMB4 Reveals Significant Upregulation, Different Expression and Association with Proliferation in Human Pulmonary Neuroendocrine TumoursMultiple-integrations of HPV16 genome and altered transcription of viral oncogenes and cellular genes are associated with the development of cervical cancerRole of the ubiquitin system and tumor viruses in AIDS-related cancer.HPV E6, E6AP and cervical cancer.The ubiquitin system, disease, and drug discovery.Potent anti-tumor effect generated by a novel human papillomavirus (HPV) antagonist peptide reactivating the pRb/E2F pathway.Human papillomavirus E7 requires the protease calpain to degrade the retinoblastoma protein.Overexpression of p28/gankyrin in human hepatocellular carcinoma and its clinical significanceHuman papillomaviruses and the interferon responseThree regions of the pRB pocket domain affect its inactivation by human papillomavirus E7 proteins.Pathogenesis of human papillomaviruses in differentiating epithelia.E6-associated transcription patterns in human papilloma virus 16-positive cervical tissuesDocosahexaenoic acid induces the degradation of HPV E6/E7 oncoproteins by activating the ubiquitin-proteasome system.Deregulation of eIF4E: 4E-BP1 in differentiated human papillomavirus-containing cells leads to high levels of expression of the E7 oncoprotein.Mechanisms underlying fibronectin-induced up-regulation of P2X4R expression in microglia: distinct roles of PI3K-Akt and MEK-ERK signalling pathwaysNonconserved lysine residues attenuate the biological function of the low-risk human papillomavirus E7 proteinStabilization of the retinoblastoma protein by A-type nuclear lamins is required for INK4A-mediated cell cycle arrestGeneration of affibody molecules specific for HPV16 E7 recognitionA Novel Retinoblastoma Protein (RB) E3 Ubiquitin Ligase (NRBE3) Promotes RB Degradation and Is Transcriptionally Regulated by E2F1 Transcription Factor.The Fanconi anemia pathway: repairing the link between DNA damage and squamous cell carcinoma.Phase II 2-arm trial of the proteasome inhibitor, PS-341 (bortezomib) in combination with irinotecan or PS-341 alone followed by the addition of irinotecan at time of progression in patients with locally recurrent or metastatic squamous cell carcinoNutlin-3 affects expression and function of retinoblastoma protein: role of retinoblastoma protein in cellular response to nutlin-3.Destabilization of Rb by human papillomavirus E7 is cell cycle dependent: E2-25K is involved in the proteolysis.Marine Streptomyces sp. derived antimycin analogues suppress HeLa cells via depletion HPV E6/E7 mediated by ROS-dependent ubiquitin-proteasome system.The papillomavirus E7 oncoprotein is ubiquitinated by UbcH7 and Cullin 1- and Skp2-containing E3 ligase.Simvastatin and Atorvastatin inhibit DNA replication licensing factor MCM7 and effectively suppress RB-deficient tumors growth.Viral takeover of the host ubiquitin system.Therapeutic targeting of cancer cell cycle using proteasome inhibitorsThe role of ubiquitin and ubiquitin-like modification systems in papillomavirus biology.Genetic susceptibility to cervical cancer: role of common polymorphisms in apoptosis-related genes.Suppression of RAD21 Induces Senescence of MDA-MB-231 Human Breast Cancer Cells Through RB1 Pathway Activation Via c-Myc Downregulation.The human papillomavirus E7 oncoprotein as a regulator of transcription.MicroRNAs in HPV associated cancers: small players with big consequences.p53-independent pRB degradation contributes to a drug-induced apoptosis in AGS cells.The HTLV-I Tax oncoprotein targets the retinoblastoma protein for proteasomal degradation.
P2860
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P2860
Both Rb and E7 are regulated by the ubiquitin proteasome pathway in HPV-containing cervical tumor cells.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年学术文章
@wuu
2001年学术文章
@zh-cn
2001年学术文章
@zh-hans
2001年学术文章
@zh-my
2001年学术文章
@zh-sg
2001年學術文章
@yue
2001年學術文章
@zh
2001年學術文章
@zh-hant
name
Both Rb and E7 are regulated b ...... ntaining cervical tumor cells.
@en
type
label
Both Rb and E7 are regulated b ...... ntaining cervical tumor cells.
@en
prefLabel
Both Rb and E7 are regulated b ...... ntaining cervical tumor cells.
@en
P2093
P2860
P356
P1433
P1476
Both Rb and E7 are regulated b ...... ntaining cervical tumor cells.
@en
P2093
P2860
P2888
P304
P356
10.1038/SJ.ONC.1204655
P407
P577
2001-08-01T00:00:00Z
P5875
P6179
1033055382