In vitro nuclear import of snRNPs: cytosolic factors mediate m3G-cap dependence of U1 and U2 snRNP transport.
about
A novel genetic screen for snRNP assembly factors in yeast identifies a conserved protein, Sad1p, also required for pre-mRNA splicingThe snoRNA box C/D motif directs nucleolar targeting and also couples snoRNA synthesis and localization.Snurportin1, an m3G-cap-specific nuclear import receptor with a novel domain structureOngoing U snRNP biogenesis is required for the integrity of Cajal bodiesCross-talk between snurportin1 subdomains.Assembly, nuclear import and function of U7 snRNPs studied by microinjection of synthetic U7 RNA into Xenopus oocytesSMN, the spinal muscular atrophy protein, forms a pre-import snRNP complex with snurportin1 and importin betaIntranuclear binding kinetics and mobility of single native U1 snRNP particles in living cells.An in vitro assay for entry into cilia reveals unique properties of the soluble diffusion barrierHigh intranuclear mobility and dynamic clustering of the splicing factor U1 snRNP observed by single particle tracking.The box C/D motif directs snoRNA 5'-cap hypermethylation.Conserved boxes C and D are essential nucleolar localization elements of U14 and U8 snoRNAs.Nucleolar localization elements in U8 snoRNA differ from sequences required for rRNA processingNucleolar accumulation of poly (A)+ RNA in heat-shocked yeast cells: implication of nucleolar involvement in mRNA transport.Characterization of the highly divergent U2 RNA homolog in the microsporidian Vairimorpha necatrix.Importin beta-depending nuclear import pathways: role of the adapter proteins in the docking and releasing steps.Nuclear import of plasmid DNA in digitonin-permeabilized cells requires both cytoplasmic factors and specific DNA sequencesThe spinal muscular atrophy disease gene product, SMN: A link between snRNP biogenesis and the Cajal (coiled) body.RNA-mediated interaction of Cajal bodies and U2 snRNA genes.Nucleolar localization elements of Xenopus laevis U3 small nucleolar RNA.Identification and characterization of Drosophila Snurportin reveals a role for the import receptor Moleskin/importin-7 in snRNP biogenesisA common maturation pathway for small nucleolar RNAs.In vitro and in vivo evidence that protein and U1 snRNP nuclear import in somatic cells differ in their requirement for GTP-hydrolysis, Ran/TC4 and RCC1Splinkerettes--improved vectorettes for greater efficiency in PCR walking.Nuclear localization signals overlap DNA- or RNA-binding domains in nucleic acid-binding proteins.The importin-beta binding domain of snurportin1 is responsible for the Ran- and energy-independent nuclear import of spliceosomal U snRNPs in vitroCellular cofactors of lentiviral integrase: from target validation to drug discovery.Nuclear import of U snRNPs requires importin betaNuclear transport of U1 snRNP in somatic cells: differences in signal requirement compared with Xenopus laevis oocytesGemin4 is an essential gene in mice, and its overexpression in human cells causes relocalization of the SMN complex to the nucleoplasm.
P2860
Q22008761-9BD06443-4BFC-45AE-BEF0-36866123D93FQ22066055-5746204F-7FA7-4735-B4D0-1AF0FE58F6FEQ24316296-4DF1E05A-9D51-4554-8233-A49B1843F5E8Q24336921-B4E0BECC-50CC-4F1F-B292-9830A290A2E5Q24536213-7B7EAED9-9DA1-414A-A3B2-3CFC2D1CA838Q24624098-F578D61E-E685-4AAF-A32B-B8771DA6921DQ24676334-840F6D9E-8CC6-449B-A89C-C26C903EE416Q30478401-E72291F5-FC26-4B34-A3F7-11ACC7C7FC94Q30551311-DC33CD62-72D8-4515-BFA6-C3BA618909E3Q31015158-728C9394-BE07-4FF4-B10D-05627489AC50Q33834044-780214E6-C7C2-4D4A-9949-9F85A7EEA183Q33888910-6A722766-EBE3-4E31-9080-9E5B49606379Q34361453-4E113981-D8CD-44AB-9498-FF6C15BE3CF5Q34452986-B93C9B72-FE31-4C45-BCDB-A3CCE1842D3FQ34589111-E054244C-8F16-42FB-8018-B61253A8807EQ35153638-8D233C46-C211-4054-9E7C-4406DB0B811EQ35428699-CF8350D0-09B8-4DDD-A291-E9B21AEFB4B5Q36301531-6984BC1C-D4A3-4464-9E87-9A93D86E7B09Q36377543-7F185863-E59B-4C21-916A-4AD3780EC471Q36917526-B17D664D-74A4-49F6-8EEF-BB14E4171997Q37167931-63972136-B4B6-46E6-A0C0-8258E0CFCD37Q37623485-9F40B073-72F9-45DC-ADC2-93C255612F47Q39716299-C2B1C04F-EBA3-4C1E-87CA-D60AD2377EF9Q40393976-C3C38014-C6CF-410E-A69C-2240D8D1D4A3Q40394004-AB0E47AB-14F4-4913-839E-2EBA4E87C072Q41889373-0656B616-A879-432C-BBB8-EFA40022A077Q42277905-3B6ED968-8BBA-49FD-9F54-C6A4FFBDA4F7Q42632635-52DFDBC2-3E5A-402E-8FF8-8613FE5F3A3CQ42770666-87A309D3-4A86-447A-B7BE-3A72E2562E09Q48163982-95C09BEB-580B-43E2-A7E3-A14CD25C1B08
P2860
In vitro nuclear import of snRNPs: cytosolic factors mediate m3G-cap dependence of U1 and U2 snRNP transport.
description
1994 nî lūn-bûn
@nan
1994年の論文
@ja
1994年学术文章
@wuu
1994年学术文章
@zh-cn
1994年学术文章
@zh-hans
1994年学术文章
@zh-my
1994年学术文章
@zh-sg
1994年學術文章
@yue
1994年學術文章
@zh
1994年學術文章
@zh-hant
name
In vitro nuclear import of snR ...... of U1 and U2 snRNP transport.
@en
type
label
In vitro nuclear import of snR ...... of U1 and U2 snRNP transport.
@en
prefLabel
In vitro nuclear import of snR ...... of U1 and U2 snRNP transport.
@en
P2860
P1433
P1476
In vitro nuclear import of snR ...... e of U1 and U2 snRNP transport
@en
P2093
Lührmann R
Marshallsay C
P2860
P304
P356
10.1002/J.1460-2075.1994.TB06252.X
P407
P577
1994-01-01T00:00:00Z