Glycosylation increases potassium channel stability and surface expression in mammalian cells.
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Antibody-based protein profiling of the human chromosome 21Reciprocal modulation between the alpha and beta 4 subunits of hSlo calcium-dependent potassium channelsDeglycosylation altered the gating properties of rNav1.3: glycosylation/deglycosylation homeostasis probably complicates the functional regulation of voltage-gated sodium channelHomo- and heterotetrameric architecture of the epithelial Ca2+ channels TRPV5 and TRPV6.Models of the structure and voltage-gating mechanism of the shaker K+ channel.Short-term regulation of organic anion transportersTargeting potassium channels in cancerDo defects in ion channel glycosylation set the stage for lethal cardiac arrhythmias?Voltage sensor mutations differentially target misfolded K+ channel subunits to proteasomal and non-proteasomal disposal pathways.Distance measurements reveal a common topology of prokaryotic voltage-gated ion channels in the lipid bilayerChemical control of metabolically-engineered voltage-gated K+ channels.Mining the virgin land of neurotoxicology: a novel paradigm of neurotoxic peptides action on glycosylated voltage-gated sodium channels.Mechanisms contributing to myocardial potassium channel diversity, regulation and remodelingMechanisms of cardiac potassium channel trafficking.Trafficking dynamics of glycosylated pannexin 1 proteinsNerve growth factor/p75 neurotrophin receptor-mediated sensitization of rat sensory neurons depends on membrane cholesterol.Glycosylation of TRPM4 and TRPM5 channels: molecular determinants and functional aspects.Protein folding in the endoplasmic reticulumMembrane targeting of ATP-sensitive potassium channel. Effects of glycosylation on surface expression.Cell surface targeting and clustering interactions between heterologously expressed PSD-95 and the Shal voltage-gated potassium channel, Kv4.2.Glycosylation increases the thermostability of human aquaporin 10 protein.Functional roles of the Ca2+-activated K+ channel, KCa3.1, in brain tumors.Cell type-specific glycosylation of Orai1 modulates store-operated Ca2+ entry.Degradation of trafficking-defective long QT syndrome type II mutant channels by the ubiquitin-proteasome pathway.Glycosylation of asparagines 136 and 184 is necessary for the alpha2delta subunit-mediated regulation of voltage-gated Ca2+ channels.The paranodal complex of F3/contactin and caspr/paranodin traffics to the cell surface via a non-conventional pathway.N-linked protein glycosylation is a major determinant for basal TRPC3 and TRPC6 channel activity.Differential effects of N-linked glycosylation of Vstm5 at multiple sites on surface expression and filopodia formation.A rare schizophrenia risk variant of CACNA1I disrupts CaV3.3 channel activity.Glycosylation affects rat Kv1.1 potassium channel gating by a combined surface potential and cooperative subunit interaction mechanism.Mammalian plasma membrane ecto-nucleoside triphosphate diphosphohydrolase 1, CD39, is not active intracellularly. The N-glycosylation state of CD39 correlates with surface activity and localization.Glycosylation affects the protein stability and cell surface expression of Kv1.4 but Not Kv1.1 potassium channels. A pore region determinant dictates the effect of glycosylation on trafficking.Assembly, maturation, and turnover of K(ATP) channel subunits.Glycosylation of Eag1 (Kv10.1) potassium channels: intracellular trafficking and functional consequences.Demonstration of ion channel synthesis by isolated squid giant axon provides functional evidence for localized axonal membrane protein translation.
P2860
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P2860
Glycosylation increases potassium channel stability and surface expression in mammalian cells.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年学术文章
@wuu
2001年学术文章
@zh-cn
2001年学术文章
@zh-hans
2001年学术文章
@zh-my
2001年学术文章
@zh-sg
2001年學術文章
@yue
2001年學術文章
@zh
2001年學術文章
@zh-hant
name
Glycosylation increases potass ...... expression in mammalian cells.
@en
type
label
Glycosylation increases potass ...... expression in mammalian cells.
@en
prefLabel
Glycosylation increases potass ...... expression in mammalian cells.
@en
P2093
P2860
P356
P1476
Glycosylation increases potass ...... expression in mammalian cells.
@en
P2093
P2860
P304
34028-34034
P356
10.1074/JBC.M105248200
P407
P577
2001-06-26T00:00:00Z