about
Implication of IRF4 aberrant gene expression in the acute leukemias of childhoodCBX8, a polycomb group protein, is essential for MLL-AF9-induced leukemogenesisGSK-3 promotes conditional association of CREB and its coactivators with MEIS1 to facilitate HOX-mediated transcription and oncogenesisIdentification and characterization of Hoxa9 binding sites in hematopoietic cellsRole of HOXA9 in leukemia: dysregulation, cofactors and essential targetsEffects of the NUP98-DDX10 oncogene on primary human CD34+ cells: role of a conserved helicase motifTaking a Bad Turn: Compromised DNA Damage Response in LeukemiaC/EBPα is an essential collaborator in Hoxa9/Meis1-mediated leukemogenesisMLL-AF9 and MLL-ENL alter the dynamic association of transcriptional regulators with genes critical for leukemia.Down-regulation of homeobox genes MEIS1 and HOXA in MLL-rearranged acute leukemia impairs engraftment and reduces proliferationTranscriptome Profiling of Pediatric Core Binding Factor AML.Up-regulation of a HOXA-PBX3 homeobox-gene signature following down-regulation of miR-181 is associated with adverse prognosis in patients with cytogenetically abnormal AML.An insertional mutagenesis screen identifies genes that cooperate with Mll-AF9 in a murine leukemogenesis model.Two isoforms of HOXA9 function differently but work synergistically in human MLL-rearranged leukemia.miR-196b directly targets both HOXA9/MEIS1 oncogenes and FAS tumour suppressor in MLL-rearranged leukaemia.PBX3 is an important cofactor of HOXA9 in leukemogenesis.To Be Specific or Not: The Critical Relationship Between Hox And TALE Proteins.Deregulation of the HOXA9/MEIS1 axis in acute leukemia.Disruption of HOX activity leads to cell death that can be enhanced by the interference of iron uptake in malignant B cells.H2.0-like homeobox regulates early hematopoiesis and promotes acute myeloid leukemiaHLX in AML: novel prognostic and therapeutic target.MicroRNA-182 downregulates Wnt/β-catenin signaling, inhibits proliferation, and promotes apoptosis in human osteosarcoma cells by targeting HOXA9.
P2860
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P2860
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
@zh
2008年學術文章
@zh-hant
name
HOX proteins and leukemia.
@en
type
label
HOX proteins and leukemia.
@en
prefLabel
HOX proteins and leukemia.
@en
P2093
P2860
P1476
HOX proteins and leukemia
@en
P2093
Jay L Hess
Kajal V Sitwala
Monisha N Dandekar
P2860
P304
P577
2008-03-30T00:00:00Z