Insulin-stimulated activation of eNOS is independent of Ca2+ but requires phosphorylation by Akt at Ser(1179).
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Protein kinase Cα phosphorylates a novel argininosuccinate synthase site at serine 328 during calcium-dependent stimulation of endothelial nitric-oxide synthase in vascular endothelial cellsApplication of 4,5-diaminofluorescein to reliably measure nitric oxide released from endothelial cellsin vitroVanadyl sulfate inhibits NO production via threonine phosphorylation of eNOS.Role of ROS and RNS Sources in Physiological and Pathological ConditionsSelective Insulin Resistance in the KidneyTargeting inflammation in diabetes: Newer therapeutic optionsInflammation and oxidative stress in diabetic nephropathy: new insights on its inhibition as new therapeutic targetsVascular and metabolic actions of the green tea polyphenol epigallocatechin gallateThe vascular endothelium in diabetes and its potential as a therapeutic target.Role of lipotoxicity in endothelial dysfunctionChanges in eNOS phosphorylation contribute to increased arteriolar NO release during juvenile growthThe insulin-like growth factor-1 receptor is a negative regulator of nitric oxide bioavailability and insulin sensitivity in the endotheliumReceptor-mediated activation of nitric oxide synthesis by arginine in endothelial cellsGenetic Variation in the Human SORBS1 Gene is Associated With Blood Pressure Regulation and Age at Onset of Hypertension: A SAPPHIRe Cohort StudyEndothelial nitric oxide synthase in the microcirculation.Twenty-five years since the discovery of endothelium-derived relaxing factor (EDRF): does a dysfunctional endothelium contribute to the development of type 2 diabetes?Adiponectin and insulin cross talk: the microvascular connection.Insulin regulates its own delivery to skeletal muscle by feed-forward actions on the vasculature.The trafficking/interaction of eNOS and caveolin-1 induced by insulin modulates endothelial nitric oxide productionObesity blunts microvascular recruitment in human forearm muscle after a mixed meal.Insulin and insulin-like growth factor-I receptors differentially mediate insulin-stimulated adhesion molecule production by endothelial cells.The vascular actions of insulin control its delivery to muscle and regulate the rate-limiting step in skeletal muscle insulin actionActive role for the vasculature in the delivery of insulin to skeletal muscle.ICAM-1-mediated endothelial nitric oxide synthase activation via calcium and AMP-activated protein kinase is required for transendothelial lymphocyte migration.Identification of regulatory sites of phosphorylation of the bovine endothelial nitric-oxide synthase at serine 617 and serine 635.Molecular mechanisms of diabetic vascular complicationsAdiponectin resistance and vascular dysfunction in the hyperlipidemic stateBeneficial effect of the oligomerized polyphenol oligonol on high glucose-induced changes in eNOS phosphorylation and dephosphorylation in endothelial cellsEnhancement of insulin responsiveness by nitric oxide-mediated inactivation of protein-tyrosine phosphatases.Bifidobacterium pseudocatenulatum CECT 7765 supplementation restores altered vascular function in an experimental model of obese miceSildenafil reduces insulin-resistance in human endothelial cellsMechanisms for food polyphenols to ameliorate insulin resistance and endothelial dysfunction: therapeutic implications for diabetes and its cardiovascular complicationsMild mitochondrial uncoupling and calorie restriction increase fasting eNOS, akt and mitochondrial biogenesisInsulin resistance, lipotoxicity, type 2 diabetes and atherosclerosis: the missing links. The Claude Bernard Lecture 2009Activation of protein kinase C isoforms and its impact on diabetic complications.Reduced hepatic eNOS phosphorylation is associated with NAFLD and type 2 diabetes progression and is prevented by daily exercise in hyperphagic OLETF ratsEndothelial dysfunction in diabetes mellitus: molecular mechanisms and clinical implications.Targeting mitochondria to restore failed adaptation to exercise in diabetes.Inactivation of phosphorylated endothelial nitric oxide synthase (Ser-1177) by O-GlcNAc in diabetes-associated erectile dysfunctionInsulin inhibits low oxygen-induced ATP release from human erythrocytes: implication for vascular control.
P2860
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P2860
Insulin-stimulated activation of eNOS is independent of Ca2+ but requires phosphorylation by Akt at Ser(1179).
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年学术文章
@wuu
2001年学术文章
@zh-cn
2001年学术文章
@zh-hans
2001年学术文章
@zh-my
2001年学术文章
@zh-sg
2001年學術文章
@yue
2001年學術文章
@zh
2001年學術文章
@zh-hant
name
Insulin-stimulated activation ...... orylation by Akt at Ser(1179).
@en
type
label
Insulin-stimulated activation ...... orylation by Akt at Ser(1179).
@en
prefLabel
Insulin-stimulated activation ...... orylation by Akt at Ser(1179).
@en
P356
P1476
Insulin-stimulated activation ...... horylation by Akt at Ser(1179)
@en
P304
30392-30398
P356
10.1074/JBC.M103702200
P407
P577
2001-06-11T00:00:00Z