Effect of mutation and phosphorylation of type I keratins on their caspase-mediated degradation.
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Keratin 20 serine 13 phosphorylation is a stress and intestinal goblet cell markerPost-translational modifications of intermediate filament proteins: mechanisms and functionsBiomarkers of systemic lupus erythematosus identified using mass spectrometry-based proteomics: a systematic reviewKeratin 8 phosphorylation by p38 kinase regulates cellular keratin filament reorganization: modulation by a keratin 1-like disease causing mutationSUMO regulates the assembly and function of a cytoplasmic intermediate filament protein in C. elegansFunctional module search in protein networks based on semantic similarity improves the analysis of proteomics data.Phosphorylation of cytokeratin 17 by herpes simplex virus type 2 US3 protein kinase.Analysis of the Rana catesbeiana tadpole tail fin proteome and phosphoproteome during T3-induced apoptosis: identification of a novel type I keratin.Keratin 8 expression in head and neck epithelia.Serum cytokeratin 19 fragment, CK19-2G2, as a newly identified biomarker for lung cancer.Defining the properties of the nonhelical tail domain in type II keratin 5: insight from a bullous disease-causing mutationKeratin hypersumoylation alters filament dynamics and is a marker for human liver disease and keratin mutation.Intermediate filaments control the intracellular distribution of caspases during apoptosis.Cell death and cell death responses in liver disease: mechanisms and clinical relevanceMolecular aetiology and pathogenesis of basal cell carcinoma.Providing cellular signposts--post-translational modifications of intermediate filaments.Caspase cleavage of GFAP produces an assembly-compromised proteolytic fragment that promotes filament aggregation.Structure and functions of keratin proteins in simple, stratified, keratinized and cornified epithelia.Mechanism-based bioanalysis and biomarkers for hepatic chemical stress.Cytokeratin immunoreactivity in lobular intraepithelial neoplasia.Mutation of caspase-digestion sites in keratin 18 interferes with filament reorganization, and predisposes to hepatocyte necrosis and loss of membrane integrity.Keratins in colorectal epithelial function and disease.Deficiency of filaggrin regulates endogenous cysteine protease activity, leading to impaired skin barrier function.Keratins: Biomarkers and modulators of apoptotic and necrotic cell death in the liver.Cell detachment and apoptosis induction of immortalized human prostate epithelial cells are associated with early accumulation of a 45 kDa nuclear isoform of clusterinCaspase proteolysis of desmin produces a dominant-negative inhibitor of intermediate filaments and promotes apoptosis.Phosphoprotein Keratin 23 accumulates in MSS but not MSI colon cancers in vivo and impacts viability and proliferation in vitro.High-mobility group box-1 protein and keratin-18, circulating serum proteins informative of acetaminophen-induced necrosis and apoptosis in vivo.Hyposmotic stress induces cell growth arrest via proteasome activation and cyclin/cyclin-dependent kinase degradation.A mutation in keratin 18 that causes caspase-digestion resistance protects homozygous transgenic mice from hepatic apoptosis and injury.Differential expression of intermediate filaments in the process of developing hepatic steatosis.
P2860
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P2860
Effect of mutation and phosphorylation of type I keratins on their caspase-mediated degradation.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
2001年论文
@zh
2001年论文
@zh-cn
name
Effect of mutation and phospho ...... caspase-mediated degradation.
@en
type
label
Effect of mutation and phospho ...... caspase-mediated degradation.
@en
prefLabel
Effect of mutation and phospho ...... caspase-mediated degradation.
@en
P2860
P356
P1476
Effect of mutation and phospho ...... r caspase-mediated degradation
@en
P2093
P2860
P304
26792-26798
P356
10.1074/JBC.M103315200
P407
P50
P577
2001-05-16T00:00:00Z