Two distinct 4-hydroxynonenal metabolizing glutathione S-transferase isozymes are differentially expressed in human tissues.
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Antioxidative function and substrate specificity of NAD(P)H-dependent alkenal/one oxidoreductase. A new role for leukotriene B4 12-hydroxydehydrogenase/15-oxoprostaglandin 13-reductaseDifferential metabolism of 4-hydroxynonenal in liver, lung and brain of mice and rats.Transfection with 4-hydroxynonenal-metabolizing glutathione S-transferase isozymes leads to phenotypic transformation and immortalization of adherent cells.Increased 4-hydroxynonenal protein adducts in male GSTA4-4/PPAR-α double knockout mice enhance injury during early stages of alcoholic liver disease.Interactions of glutathione transferases with 4-hydroxynonenal.Afferent regulation of oxidative stress in the chick cochlear nucleus.Antioxidant role of glutathione S-transferases: 4-Hydroxynonenal, a key molecule in stress-mediated signalingLoss of glutathione S-transferase A4 accelerates obstruction-induced tubule damage and renal fibrosisGsta4 Null Mouse Embryonic Fibroblasts Exhibit Enhanced Sensitivity to Oxidants: Role of 4-Hydroxynonenal in Oxidant Toxicity.Emerging role of thiamine therapy for prevention and treatment of early-stage diabetic nephropathy.Membrane association of glutathione S-transferase mGSTA4-4, an enzyme that metabolizes lipid peroxidation products.Mitogenic and drug-resistance mediating effects of PKCalpha require RLIP76.4-Hydroxynonenal induces p53-mediated apoptosis in retinal pigment epithelial cells.Cells preconditioned with mild, transient UVA irradiation acquire resistance to oxidative stress and UVA-induced apoptosis: role of 4-hydroxynonenal in UVA-mediated signaling for apoptosis.Danshen protects against early-stage alcoholic liver disease in mice via inducing PPARα activation and subsequent 4-HNE degradation.Cloning, expression and biochemical characterization of one Epsilon-class (GST-3) and ten Delta-class (GST-1) glutathione S-transferases from Drosophila melanogaster, and identification of additional nine members of the Epsilon class.Accelerated metabolism and exclusion of 4-hydroxynonenal through induction of RLIP76 and hGST5.8 is an early adaptive response of cells to heat and oxidative stress.4-hydroxynonenal detoxification by mitochondrial glutathione S-transferase is compromised by short-term ethanol consumption in rats.Polymorphisms of the glutathione S-transferases mu-1 (GSTM1) and theta-1 (GSTT1) and the risk of advanced alcoholic liver disease.Altered growth characteristics of skin fibroblasts from wild-derived mice, and genetic loci regulating fibroblast clone size.Reduced Expression of Glutathione S-Transferase α 4 Promotes Vascular Neointimal Hyperplasia in CKD.
P2860
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P2860
Two distinct 4-hydroxynonenal metabolizing glutathione S-transferase isozymes are differentially expressed in human tissues.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
2001年论文
@zh
2001年论文
@zh-cn
name
Two distinct 4-hydroxynonenal ...... ly expressed in human tissues.
@en
type
label
Two distinct 4-hydroxynonenal ...... ly expressed in human tissues.
@en
prefLabel
Two distinct 4-hydroxynonenal ...... ly expressed in human tissues.
@en
P2093
P356
P1476
Two distinct 4-hydroxynonenal ...... ly expressed in human tissues.
@en
P2093
S S Singhal
Y C Awasthi
P304
P356
10.1006/BBRC.2001.4707
P577
2001-04-01T00:00:00Z