Cutting edge: the Wiskott-Aldrich syndrome protein is required for efficient phagocytosis of apoptotic cells.
about
Phosphorylation of tyrosine 291 enhances the ability of WASp to stimulate actin polymerization and filopodium formation. Wiskott-Aldrich Syndrome proteinA WASp-VASP complex regulates actin polymerization at the plasma membrane.The clearance of dying cells: table for twoModelling of human Wiskott-Aldrich syndrome protein mutants in zebrafish larvae using in vivo live imagingActin cytoskeletal defects in immunodeficiencyRegulation of phagocytosis by Rho GTPasesIn Vivo Chronic Stimulation Unveils Autoreactive Potential of Wiskott-Aldrich Syndrome Protein-Deficient B Cells.Monocytes from Wiskott-Aldrich patients differentiate in functional mature dendritic cells with a defect in CD83 expression.WASP deficiency leads to global defects of directed leukocyte migration in vitro and in vivo.Rapid platelet turnover in WASP(-) mice correlates with increased ex vivo phagocytosis of opsonized WASP(-) platelets.The thrombocytopenia of WAS: a familial form of ITP?Wiskott-Aldrich syndrome: a comprehensive review.Systemic autoimmunity and defective Fas ligand secretion in the absence of the Wiskott-Aldrich syndrome proteinTethering and tickling: a new role for the phosphatidylserine receptor.Effector triggered immunityWASp in immune-system organization and function.Regulation of endocytic traffic by Rho GTPases.Leukocyte uropod formation and membrane/cytoskeleton linkage in immune interactions.Impaired phagocytosis of apoptotic cells by macrophages in chronic granulomatous disease is reversed by IFN-γ in a nitric oxide-dependent mannerReduced uptake of apoptotic cells by macrophages in systemic lupus erythematosus: correlates with decreased serum levels of complementDendritic cell functional improvement in a preclinical model of lentiviral-mediated gene therapy for Wiskott-Aldrich syndromeAutoimmunity in wiskott-Aldrich syndrome: an unsolved enigma.Phagocytosis of apoptotic cells and immune regulation.Cdc42 interacts with the exocyst complex to promote phagocytosis.Wiskott-Aldrich syndrome protein-mediated actin dynamics control type-I interferon production in plasmacytoid dendritic cells.Wiskott-Aldrich Syndrome at the nexus of autoimmune and primary immunodeficiency diseases.Contribution of histidine-rich glycoprotein in clearance of immune complexes and apoptotic cells: implications for ameliorating autoimmune diseases.WASP confers selective advantage for specific hematopoietic cell populations and serves a unique role in marginal zone B-cell homeostasis and function.Reduced type I interferon production by dendritic cells and weakened antiviral immunity in patients with Wiskott-Aldrich syndrome protein deficiencyBreakdown of T cell tolerance and autoimmunity in primary immunodeficiency--lessons learned from monogenic disorders in mice and menPhosphorylation of WASp is a key regulator of activity and stability in vivo.Novel anti-HIV therapeutics targeting chemokine receptors and actin regulatory pathwaysWiskott-Aldrich Syndrome: Immunodeficiency resulting from defective cell migration and impaired immunostimulatory activationImmune pathology associated with altered actin cytoskeleton regulation.Prix Fixe: Efferocytosis as a Four-Course Meal.Antagonistic cross-talk between Rac and Cdc42 GTPases regulates generation of reactive oxygen species.Wiskott-Aldrich syndrome protein is needed for vaccinia virus pathogenesis.Class I phosphoinositide 3-kinase p110beta is required for apoptotic cell and Fcgamma receptor-mediated phagocytosis by macrophages.Wiskott-Aldrich syndrome caused by a new mutation associated with multifocal dermal juvenile xanthogranulomas.Wiskott-Aldrich syndrome protein regulates autophagy and inflammasome activity in innate immune cells.
P2860
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P2860
Cutting edge: the Wiskott-Aldrich syndrome protein is required for efficient phagocytosis of apoptotic cells.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
2001年论文
@zh
2001年论文
@zh-cn
name
Cutting edge: the Wiskott-Aldr ...... agocytosis of apoptotic cells.
@en
type
label
Cutting edge: the Wiskott-Aldr ...... agocytosis of apoptotic cells.
@en
prefLabel
Cutting edge: the Wiskott-Aldr ...... agocytosis of apoptotic cells.
@en
P2093
P1476
Cutting edge: the Wiskott-Aldr ...... agocytosis of apoptotic cells.
@en
P2093
Blundell MP
Brickell P
Thrasher AJ
P304
P356
10.4049/JIMMUNOL.166.8.4831
P407
P577
2001-04-01T00:00:00Z