Interaction between human immunodeficiency virus type 1 reverse transcriptase and integrase proteins.
about
Importin alpha3 interacts with HIV-1 integrase and contributes to HIV-1 nuclear import and replicationBroad antiretroviral activity and resistance profile of the novel human immunodeficiency virus integrase inhibitor elvitegravir (JTK-303/GS-9137)Contribution of the C-terminal tri-lysine regions of human immunodeficiency virus type 1 integrase for efficient reverse transcription and viral DNA nuclear importA novel function for spumaretrovirus integrase: an early requirement for integrase-mediated cleavage of 2 LTR circles.HIV Genome-Wide Protein Associations: a Review of 30 Years of ResearchCrystal structure of the HIV-1 integrase core domain in complex with sucrose reveals details of an allosteric inhibitory binding siteRetroviral Integrase: Then and NowConservation patterns of HIV-1 RT connection and RNase H domains: identification of new mutations in NRTI-treated patientsNon-catalytic site HIV-1 integrase inhibitors disrupt core maturation and induce a reverse transcription block in target cellsRetroviral DNA IntegrationStructural dynamics of native and V260E mutant C-terminal domain of HIV-1 integrase.Biochemical and virological analysis of the 18-residue C-terminal tail of HIV-1 integrase.Requirement for integrase during reverse transcription of human immunodeficiency virus type 1 and the effect of cysteine mutations of integrase on its interactions with reverse transcriptase.Structural basis for HIV-1 DNA integration in the human genome, role of the LEDGF/P75 cofactorAugmentation of reverse transcription by integrase through an interaction with host factor, SIP1/Gemin2 Is critical for HIV-1 infection.Peptides derived from the reverse transcriptase of human immunodeficiency virus type 1 as novel inhibitors of the viral integrase.Revealing domain structure through linker-scanning analysis of the murine leukemia virus (MuLV) RNase H and MuLV and human immunodeficiency virus type 1 integrase proteinsRecruitment of a SAP18-HDAC1 complex into HIV-1 virions and its requirement for viral replicationPeptide HIV-1 integrase inhibitors from HIV-1 gene products.Peptidic HIV integrase inhibitors derived from HIV gene products: structure-activity relationship studies.Changes in the accessibility of the HIV-1 Integrase C-terminus in the presence of cellular proteins.Mechanisms and inhibition of HIV integrationRole of human immunodeficiency virus type 1 integrase in uncoating of the viral core.Mutations that abrogate human immunodeficiency virus type 1 reverse transcriptase dimerization affect maturation of the reverse transcriptase heterodimer.Altered viral fitness and drug susceptibility in HIV-1 carrying mutations that confer resistance to nonnucleoside reverse transcriptase and integrase strand transfer inhibitors.A Leu to Ile but not Leu to Val change at HIV-1 reverse transcriptase codon 74 in the background of K65R mutation leads to an increased processivity of K65R+L74I enzyme and a replication competent virus.Analysis of HIV-1 replication block due to substitutions at F61 residue of reverse transcriptase reveals additional defects involving the RNase H functionThe self primer of the long terminal repeat retrotransposon Tf1 is not removed during reverse transcription.Impairment of human immunodeficiency virus type-1 integrase SUMOylation correlates with an early replication defect.HIV-1 replication in cell lines harboring INI1/hSNF5 mutations.Retroviral DNA Transposition: Themes and VariationsReverse Transcriptase and Cellular Factors: Regulators of HIV-1 Reverse Transcription.Human immunodeficiency virus type 1 employs the cellular dynein light chain 1 protein for reverse transcription through interaction with its integrase proteinReduced viral fitness and lack of cross-class resistance with integrase strand transfer inhibitor and nucleoside reverse transcriptase inhibitor resistance mutationsIncorporation of human immunodeficiency virus type 1 reverse transcriptase into virus-like particlesvon Hippel Lindau binding protein 1-mediated degradation of integrase affects HIV-1 gene expression at a postintegration step.Molecular mechanisms by which human immunodeficiency virus type 1 integrase stimulates the early steps of reverse transcription.Interaction between Reverse Transcriptase and Integrase Is Required for Reverse Transcription during HIV-1 Replication.A protein ballet around the viral genome orchestrated by HIV-1 reverse transcriptase leads to an architectural switch: from nucleocapsid-condensed RNA to Vpr-bridged DNA.Molecular Docking and Molecular Dynamics to Identify a Novel Human Immunodeficiency Virus Inhibitor from Alkaloids of Toddalia asiatica.
P2860
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P2860
Interaction between human immunodeficiency virus type 1 reverse transcriptase and integrase proteins.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
Interaction between human immu ...... iptase and integrase proteins.
@en
type
label
Interaction between human immu ...... iptase and integrase proteins.
@en
prefLabel
Interaction between human immu ...... iptase and integrase proteins.
@en
P2093
P2860
P1433
P1476
Interaction between human immu ...... iptase and integrase proteins.
@en
P2093
Eric A Hehl
Ganjam V Kalpana
Pheroze Joshi
P2860
P304
P356
10.1128/JVI.78.10.5056-5067.2004
P407
P577
2004-05-01T00:00:00Z