Deep Sequencing-guided Design of a High Affinity Dual Specificity Antibody to Target Two Angiogenic Factors in Neovascular Age-related Macular Degeneration.
about
Tuning the specificity of a Two-in-One Fab against three angiogenic antigens by fully utilizing the information of deep mutational scanning.Mutational landscape of antibody variable domains reveals a switch modulating the interdomain conformational dynamics and antigen binding.Affinity Maturation of a Cyclic Peptide Handle for Therapeutic Antibodies Using Deep Mutational Scanning.Deep sequencing methods for protein engineering and design.Hierarchical design of artificial proteins and complexes toward synthetic structural biology.A multispecific monoclonal antibody G2 recognizes at least three completely different epitope sequences with high affinity.Mapping protein selectivity landscapes using multi-target selective screening and next-generation sequencing of combinatorial libraries
P2860
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P2860
Deep Sequencing-guided Design of a High Affinity Dual Specificity Antibody to Target Two Angiogenic Factors in Neovascular Age-related Macular Degeneration.
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
Deep Sequencing-guided Design ...... -related Macular Degeneration.
@en
type
label
Deep Sequencing-guided Design ...... -related Macular Degeneration.
@en
prefLabel
Deep Sequencing-guided Design ...... -related Macular Degeneration.
@en
P2093
P2860
P356
P1476
Deep Sequencing-guided Design ...... -related Macular Degeneration.
@en
P2093
Chingwei V Lee
Germaine Fuh
Jeremy Stinson
Patrick Koenig
Sarah Sanowar
Seth F Harris
P2860
P304
21773-21786
P356
10.1074/JBC.M115.662783
P407
P577
2015-06-18T00:00:00Z