The triage of damaged proteins: degradation by the ubiquitin-proteasome pathway or repair by molecular chaperones.
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Docking-dependent ubiquitination of the interferon regulatory factor-1 tumor suppressor protein by the ubiquitin ligase CHIPRoles for the ubiquitin-proteasome pathway in protein quality control and signaling in the retina: implications in the pathogenesis of age-related macular degenerationAllostery in the Hsp70 chaperone proteinsHsp40 chaperones promote degradation of the HERG potassium channel.Methylglyoxal alters the function and stability of critical components of the protein quality control.The chaperone-dependent ubiquitin ligase CHIP targets HIF-1α for degradation in the presence of methylglyoxalNon-repair pathways for minimizing protein isoaspartyl damage in the yeast Saccharomyces cerevisiae.Modulatory Effect of Monochromatic Blue Light on Heat Stress Response in Commercial Broilers.Protein homeostasis and aging: The importance of exquisite quality control.Cellular senescence and protein degradation: breaking down cancerBAG3 expression in glioblastoma cells promotes accumulation of ubiquitinated clients in an Hsp70-dependent manner.Ubiquitin-proteasome pathway and cellular responses to oxidative stress.Parkin mediates the degradation-independent ubiquitination of Hsp70Molecular factors and biochemical pathways induced by febrile temperature in intraerythrocytic Plasmodium falciparum parasites.Isoform-selective Genetic Inhibition of Constitutive Cytosolic Hsp70 Activity Promotes Client Tau Degradation Using an Altered Co-chaperone ComplementDegradation of C-terminal truncated alpha A-crystallins by the ubiquitin-proteasome pathway.Enhancement of ubiquitin conjugation activity reduces intracellular aggregation of V76D mutant γD-crystallin.Dietary glycemia as a determinant of health and longevityChanges in select redox proteins of the retinal pigment epithelium in age-related macular degenerationAge- and Hypertension-Associated Protein Aggregates in Mouse Heart Have Similar Proteomic Profiles.Degradation of NF-κB, p53 and other regulatory redox-sensitive proteins by thiol-conjugating and -nitrosylating drugs in human tumor cells.Protein quality control and degradation in cardiomyocytes.A therapeutic dose of doxorubicin activates ubiquitin-proteasome system-mediated proteolysis by acting on both the ubiquitination apparatus and proteasome.In vivo suppression of polyglutamine neurotoxicity by C-terminus of Hsp70-interacting protein (CHIP) supports an aggregation model of pathogenesis.Expression and localization of Hsps in the heart and blood vessel of heat-stressed broilers.Sustained oxidative stress inhibits NF-kappaB activation partially via inactivating the proteasome.The shock of aging: molecular chaperones and the heat shock response in longevity and aging--a mini-review.Stressing the ubiquitin-proteasome system.Molecular chaperones and proteostasis regulation during redox imbalance.Proteins that accumulate with age in human skeletal-muscle aggregates contribute to declines in muscle mass and function in Caenorhabditis elegansCommon cell biologic and biochemical changes in aging and age-related diseases of the eye: toward new therapeutic approaches to age-related ocular diseasesCurrent Perspective in the Discovery of Anti-aging Agents from Natural Products.CHIP promotes human telomerase reverse transcriptase degradation and negatively regulates telomerase activity.Trimethylamine N-oxide alleviates the severe aggregation and ER stress caused by G98R alphaA-crystallin.The proteasome: a target of oxidative damage in cultured human retina pigment epithelial cells.Utility of 17-(allylamino)-17-demethoxygeldanamycin treatment for skeletal muscle injuryExpression of K6W-ubiquitin in lens epithelial cells leads to upregulation of a broad spectrum of molecular chaperones.E3 ubiquitin ligase CHIP and NBR1-mediated selective autophagy protect additively against proteotoxicity in plant stress responses.Oligomerization with wt αA- and αB-crystallins reduces proteasome-mediated degradation of C-terminally truncated αA-crystallin.Susceptibility of p53 unstructured N terminus to 20 S proteasomal degradation programs the stress response.
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P2860
The triage of damaged proteins: degradation by the ubiquitin-proteasome pathway or repair by molecular chaperones.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年学术文章
@wuu
2006年学术文章
@zh-cn
2006年学术文章
@zh-hans
2006年学术文章
@zh-my
2006年学术文章
@zh-sg
2006年學術文章
@yue
2006年學術文章
@zh
2006年學術文章
@zh-hant
name
The triage of damaged proteins ...... epair by molecular chaperones.
@en
type
label
The triage of damaged proteins ...... epair by molecular chaperones.
@en
prefLabel
The triage of damaged proteins ...... epair by molecular chaperones.
@en
P2093
P2860
P50
P356
P1433
P1476
The triage of damaged proteins ...... repair by molecular chaperones
@en
P2093
Allen Taylor
Cam Patterson
Weimin Guo
P2860
P304
P356
10.1096/FJ.05-5080FJE
P407
P577
2006-02-09T00:00:00Z