Neurodegeneration prevented by lentiviral vector delivery of GDNF in primate models of Parkinson's disease.
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The promise of neuroprotective agents in Parkinson's diseaseGlial cell line-derived neurotrophic factor reverses ethanol-mediated increases in tyrosine hydroxylase immunoreactivity via altering the activity of heat shock protein 90Calcitriol imparts neuroprotection in vitro to midbrain dopaminergic neurons by upregulating GDNF expressionSimvastatin inhibits the activation of p21ras and prevents the loss of dopaminergic neurons in a mouse model of Parkinson's diseaseAvailable and emerging treatments for Parkinson's disease: a reviewMillisecond-timescale optical control of neural dynamics in the nonhuman primate brainImaging of peripheral benzodiazepine receptor expression as biomarkers of detrimental versus beneficial glial responses in mouse models of Alzheimer's and other CNS pathologiesTargeting neural precursors in the adult brain rescues injured dopamine neuronsIdentification of unique reciprocal and non reciprocal cross packaging relationships between HIV-1, HIV-2 and SIV reveals an efficient SIV/HIV-2 lentiviral vector system with highly favourable features for in vivo testing and clinical usageTheoretical Approaches to Lentiviral Mediated Neurotrophin Delivery in Potential Treatments of Parkinson's DiseaseNeuroprotective and Therapeutic Strategies against Parkinson's Disease: Recent PerspectivesModeling Parkinson's disease in the common marmoset (Callithrix jacchus): overview of models, methods, and animal careParkinson's disease: gene therapiesThe interhemispheric connections of the striatum: Implications for Parkinson's disease and drug-induced dyskinesiasGene-based therapy of Parkinson's Disease: Translation from animal model to human clinical trial employing convection enhanced deliveryGlial-derived neurotrophic factor gene transfer for Parkinson's disease: anterograde distribution of AAV2 vectors in the primate brainTreating Parkinson's disease in the 21st century: can stem cell transplantation compete?Intrastriatal transplantation of adult human neural crest-derived stem cells improves functional outcome in parkinsonian ratsComparative Analysis of the Effects of Neurotrophic Factors CDNF and GDNF in a Nonhuman Primate Model of Parkinson's DiseaseTherapeutic potential of optogenetic neuromodulationCellular replacement therapy for Parkinson's disease--where we are today?Neurotrophic factors as a therapeutic target for Parkinson's diseaseChemicals possessing a neurotrophin-like activity on dopaminergic neurons in primary cultureThe nigrostriatal dopamine system of aging GFRalpha-1 heterozygous mice: neurochemistry, morphology and behaviorA monoclonal antibody-GDNF fusion protein is not neuroprotective and is associated with proliferative pancreatic lesions in parkinsonian monkeysIntraoperative intracerebral MRI-guided navigation for accurate targeting in nonhuman primatesEnhanced delivery and bioactivity of the neurturin neurotrophic factor through focused ultrasound-mediated blood--brain barrier opening in vivo.Neuromolecular imaging, a nanobiotechnology for Parkinson's disease: advancing pharmacotherapy for personalized medicine.Long-term consequences of methamphetamine exposure in young adults are exacerbated in glial cell line-derived neurotrophic factor heterozygous mice.Macrophage-mediated GDNF delivery protects against dopaminergic neurodegeneration: a therapeutic strategy for Parkinson's disease.Dyskinesias do not develop after chronic intermittent levodopa therapy in clinically hemiparkinsonian rhesus monkeysAutologous mesenchymal stem cell-derived dopaminergic neurons function in parkinsonian macaques.Human neural stem cells survive long term in the midbrain of dopamine-depleted monkeys after GDNF overexpression and project neurites toward an appropriate target.Autologous transplantation of GDNF-expressing mesenchymal stem cells protects against MPTP-induced damage in cynomolgus monkeysHuman gene therapy and imaging in neurological diseases.A functional dermatan sulfate epitope containing iduronate(2-O-sulfate)alpha1-3GalNAc(6-O-sulfate) disaccharide in the mouse brain: demonstration using a novel monoclonal antibody raised against dermatan sulfate of ascidian Ascidia nigra.In vivo transgene expression from an adenoviral vector is altered following a 6-OHDA lesion of the dopamine system.Delivery of sonic hedgehog or glial derived neurotrophic factor to dopamine-rich grafts in a rat model of Parkinson's disease using adenoviral vectors Increased yield of dopamine cells is dependent on embryonic donor ageGeneralized algorithms for direct reconstruction of parametric images from dynamic PET data.Transgenes delivered by lentiviral vector are suppressed in human embryonic stem cells in a promoter-dependent manner.
P2860
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P2860
Neurodegeneration prevented by lentiviral vector delivery of GDNF in primate models of Parkinson's disease.
description
2000 nî lūn-bûn
@nan
2000年の論文
@ja
2000年学术文章
@wuu
2000年学术文章
@zh-cn
2000年学术文章
@zh-hans
2000年学术文章
@zh-my
2000年学术文章
@zh-sg
2000年學術文章
@yue
2000年學術文章
@zh
2000年學術文章
@zh-hant
name
Neurodegeneration prevented by ...... models of Parkinson's disease.
@en
type
label
Neurodegeneration prevented by ...... models of Parkinson's disease.
@en
prefLabel
Neurodegeneration prevented by ...... models of Parkinson's disease.
@en
P2093
P1433
P1476
Neurodegeneration prevented by ...... models of Parkinson's disease.
@en
P2093
Aebischer P
Hantraye P
Kordower JH
P304
P356
10.1126/SCIENCE.290.5492.767
P407
P577
2000-10-01T00:00:00Z