Coexistence of TERT promoter and BRAF mutations in cutaneous melanoma is associated with more clinicopathological features of aggressiveness.
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Cancer-Specific Telomerase Reverse Transcriptase (TERT) Promoter Mutations: Biological and Clinical ImplicationsTranscription Regulation of the Human Telomerase Reverse Transcriptase (hTERT) GeneActivation of mutant TERT promoter by RAS-ERK signaling is a key step in malignant progression of BRAF-mutant human melanomas.Genetic and Epigenetic Alterations of TERT Are Associated with Inferior Outcome in Adolescent and Young Adult Patients with Melanoma.Understanding TERT Promoter Mutations: A Common Path to Immortality.TERT promoter mutations in melanoma survival.Presence of immune cells, low tumor proliferation and wild type BRAF mutation status is associated with a favourable clinical outcome in stage III cutaneous melanomaManagement of intracranial melanomas in the era of precision medicine.Telomerase reverse transcriptase promoter alterations across cancer types as detected by next-generation sequencing: A clinical and molecular analysis of 423 patients.Prognostic impact and concordance of TERT promoter mutation and protein expression in matched primary and metastatic cutaneous melanoma.Low frequency of TERT promoter mutations in a series of well-differentiated follicular-patterned thyroid neoplasms.Systemic BRAF/MEK Inhibitors as a Potential Treatment Option in Metastatic Conjunctival Melanoma.Regulation of mutant TERT by BRAF V600E/MAP kinase pathway through FOS/GABP in human cancer.Combining molecular and immunohistochemical analyses of key drivers in primary melanomas: interplay between germline and somatic variations.TERT promoter mutations and their correlation with BRAF and RAS mutations in a consecutive cohort of 145 thyroid cancer cases.In Japanese patients with papillary thyroid carcinoma, TERT promoter mutation is associated with poor prognosis, in contrast to BRAF V600E mutation.Telomere Maintenance Mechanisms in Cancer.Coexistence of Promoter Mutations and the V600E Alteration and Its Impact on Histopathological Features of Papillary Thyroid Carcinoma in a Selected Series of Polish Patients
P2860
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P2860
Coexistence of TERT promoter and BRAF mutations in cutaneous melanoma is associated with more clinicopathological features of aggressiveness.
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
Coexistence of TERT promoter a ...... al features of aggressiveness.
@en
type
label
Coexistence of TERT promoter a ...... al features of aggressiveness.
@en
prefLabel
Coexistence of TERT promoter a ...... al features of aggressiveness.
@en
P2093
P2860
P50
P1433
P1476
Coexistence of TERT promoter a ...... al features of aggressiveness.
@en
P2093
Barbara Loggini
Cristina Niccoli
Elisabetta Macerola
Giulia Garavello
Mirella Giordano
P2860
P2888
P304
P356
10.1007/S00428-015-1784-X
P577
2015-06-09T00:00:00Z
P6179
1020613663