Deoxyuridine triphosphatase (dUTPase) expression and sensitivity to the thymidylate synthase (TS) inhibitor ZD9331
about
AP endonuclease deficiency results in extreme sensitivity to thymidine deprivationRegulation of human dUTPase gene expression and p53-mediated transcriptional repression in response to oxaliplatin-induced DNA damageThe ability to accumulate deoxyuridine triphosphate and cellular response to thymidylate synthase (TS) inhibitionSMUG1 but not UNG DNA glycosylase contributes to the cellular response to recovery from 5-fluorouracil induced replication stressA novel fluorescence-based assay for the rapid detection and quantification of cellular deoxyribonucleoside triphosphates.Uracil in DNA: consequences for carcinogenesis and chemotherapy5-Fluorouracil: mechanisms of resistance and reversal strategies.Apoptosis and molecular targeting therapy in cancer.Cellular response to efficient dUTPase RNAi silencing in stable HeLa cell lines perturbs expression levels of genes involved in thymidylate metabolism.Novel opportunities for thymidylate metabolism as a therapeutic target.Uracil incorporation into genomic DNA does not predict toxicity caused by chemotherapeutic inhibition of thymidylate synthase.dUTPase inhibition augments replication defects of 5-Fluorouracil.Synthesis of certain 2'-deoxyuridine derivatives containing substituted phenoxy groups attached to C-5'; evaluation as potential dUTP analogues.Cysteine residues contribute to the dimerization and enzymatic activity of human nuclear dUTP nucleotidohydrolase (nDut)
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P2860
Deoxyuridine triphosphatase (dUTPase) expression and sensitivity to the thymidylate synthase (TS) inhibitor ZD9331
description
2000 nî lūn-bûn
@nan
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
2000年论文
@zh
2000年论文
@zh-cn
name
Deoxyuridine triphosphatase (d ...... synthase (TS) inhibitor ZD9331
@en
type
label
Deoxyuridine triphosphatase (d ...... synthase (TS) inhibitor ZD9331
@en
prefLabel
Deoxyuridine triphosphatase (d ...... synthase (TS) inhibitor ZD9331
@en
P2093
P2860
P356
P1476
Deoxyuridine triphosphatase (d ...... synthase (TS) inhibitor ZD9331
@en
P2093
Hardcastle A
Jackman AL
P2860
P2888
P304
P356
10.1054/BJOC.2000.1358
P407
P577
2000-09-01T00:00:00Z
P5875
P6179
1021368653