Ligand regulation of green fluorescent protein-tagged forms of the human beta(1)- and beta(2)-adrenoceptors; comparisons with the unmodified receptors.
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Mdm2 directs the ubiquitination of beta-arrestin-sequestered cAMP phosphodiesterase-4D5The metabotropic glutamate receptor 4 is internalized and desensitized upon protein kinase C activationDetection of receptor ligands by monitoring selective stabilization of a Renilla luciferase-tagged, constitutively active mutant, G-protein-coupled receptorbeta-Arrestin-mediated PDE4 cAMP phosphodiesterase recruitment regulates beta-adrenoceptor switching from Gs to GiHidden prenatal malnutrition in the rat: role of β₁-adrenoceptors on synaptic plasticity in the frontal cortexScanning peptide array analyses identify overlapping binding sites for the signalling scaffold proteins, beta-arrestin and RACK1, in cAMP-specific phosphodiesterase PDE4D5.Mapping binding sites for the PDE4D5 cAMP-specific phosphodiesterase to the N- and C-domains of beta-arrestin using spot-immobilized peptide arraysA novel approach to quantify G-protein-coupled receptor dimerization equilibrium using bioluminescence resonance energy transferHuman beta1-adrenergic receptor is subject to constitutive and regulated N-terminal cleavageFluorogen-activating proteins as biosensors of cell-surface proteins in living cellsCardiomyocyte lipids impair β-adrenergic receptor function via PKC activation.Redirecting lipoic acid ligase for cell surface protein labeling with small-molecule probes.Recent advances on the δ opioid receptor: from trafficking to function.Importance of a N-terminal aspartate in the internalization of the neuropeptide Y Y2 receptor.Molecular Pharmacology of δ-Opioid Receptors.Rapid recycling of beta-adrenergic receptors is dependent on the actin cytoskeleton and myosin Vb.Activation of spinal mu- and delta-opioid receptors potently inhibits substance P release induced by peripheral noxious stimuliHomo- and hetero-oligomeric interactions between G-protein-coupled receptors in living cells monitored by two variants of bioluminescence resonance energy transfer (BRET): hetero-oligomers between receptor subtypes form more efficiently than betweenFluorescent knock-in mice to decipher the physiopathological role of G protein-coupled receptors.Real-time endocytosis imaging as a rapid assay of ligand-GPCR binding in single cells.Effects of inactivation-resistant agonists on the signalling, desensitization and down-regulation of bradykinin B(2) receptors.Phosphodiesterase-4 influences the PKA phosphorylation status and membrane translocation of G-protein receptor kinase 2 (GRK2) in HEK-293beta2 cells and cardiac myocytes.RNA silencing identifies PDE4D5 as the functionally relevant cAMP phosphodiesterase interacting with beta arrestin to control the protein kinase A/AKAP79-mediated switching of the beta2-adrenergic receptor to activation of ERK in HEK293B2 cells.Resistance of the human beta1-adrenergic receptor to agonist-induced ubiquitination: a mechanism for impaired receptor degradation.The unique amino-terminal region of the PDE4D5 cAMP phosphodiesterase isoform confers preferential interaction with beta-arrestins.The Arabidopsis putative G protein-coupled receptor GCR1 interacts with the G protein alpha subunit GPA1 and regulates abscisic acid signaling.Resistance of the human beta 1-adrenergic receptor to agonist-mediated down-regulation. Role of the C terminus in determining beta-subtype degradation.Validation of a rapid, non-radioactive method to quantify internalisation of G-protein coupled receptorsPharmacological characterization of CGP 12177 at the human beta(2)-adrenoceptor.Antidepressant-induced switch of beta 1-adrenoceptor trafficking as a mechanism for drug action.GCR1 can act independently of heterotrimeric G-protein in response to brassinosteroids and gibberellins in Arabidopsis seed germination.Anti-beta1-adrenergic receptor autoantibodies in patients with chronic Chagas heart disease.
P2860
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P2860
Ligand regulation of green fluorescent protein-tagged forms of the human beta(1)- and beta(2)-adrenoceptors; comparisons with the unmodified receptors.
description
2000 nî lūn-bûn
@nan
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
2000年论文
@zh
2000年论文
@zh-cn
name
Ligand regulation of green flu ...... with the unmodified receptors.
@en
type
label
Ligand regulation of green flu ...... with the unmodified receptors.
@en
prefLabel
Ligand regulation of green flu ...... with the unmodified receptors.
@en
P2860
P356
P1476
Ligand regulation of green flu ...... with the unmodified receptors.
@en
P2093
A J McLean
G Milligan
P2860
P304
P356
10.1038/SJ.BJP.0703506
P407
P577
2000-08-01T00:00:00Z