Blocking periodontal disease progression by inhibiting tissue-destructive enzymes: a potential therapeutic role for tetracyclines and their chemically-modified analogs.
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Metalloproteinase inhibitors, nonantimicrobial chemically modified tetracyclines, and ilomastat block Bacillus anthracis lethal factor activity in viable cellsPotassium channel-blockers as therapeutic agents to interfere with bone resorption of periodontal diseaseAntimicrobial photodynamic therapy may promote periodontal healing through multiple mechanisms.Iron-chelating activity of tetracyclines and its impact on the susceptibility of Actinobacillus actinomycetemcomitans to these antibioticsPulp revascularization of replanted immature dog teeth after treatment with minocycline and doxycycline assessed by laser Doppler flowmetry, radiography, and histology.Devices for periodontal regeneration.Bone resorption caused by three periodontal pathogens in vivo in mice is mediated in part by prostaglandin.Treatment of periodontal disease and control of diabetes: an assessment of the evidence and need for future research.Matrix metalloproteinases and atherosclerotic plaque instability.The role of matrix metalloproteinases in vascular disease.Effects of long-term doxycycline on bone quality and strength in diabetic male DBA/2J miceIntraperitoneal injection of tetracyclines protects mice from lethal endotoxemia downregulating inducible nitric oxide synthase in various organs and cytokine and nitrate secretion in blood.Host-mediated resolution of inflammation in periodontal diseases.Minocycline for short-term neuroprotectionRepurposing an old drug to improve the use and safety of tissue plasminogen activator for acute ischemic stroke: minocyclineEffect of scaling and root planing combined with systemic doxycycline therapy on glycemic control in diabetes mellitus subjects with chronic generalized periodontitis: a clinical study.Periodontal pocket treatment in beagle dogs using subgingival doxycycline from a biodegradable system. I. Initial clinical responses.Inhibition of the activities of matrix metalloproteinases 2, 8, and 9 by chlorhexidine.A study on the mechanisms by which minocycline protects against MDMA ('ecstasy')-induced neurotoxicity of 5-HT cortical neurons.Critical issues in periodontal research.Modulation of bone resorption by tetracyclines.Response to periodontal therapy in diabetics and smokers.What the mouth has to say about diabetes. Careful examinations can avert serious complications.Evidence versus empiricism: rational use of systemic antimicrobial agents for treatment of periodontitis.Repurposing an old drug to improve the use and safety of tissue plasminogen activator for acute ischemic stroke: minocycline.The effect of doxycycline hyclate, chlorhexidine gluconate, and minocycline hydrochloride on osteoblastic proliferation and differentiation in vitro.Interleukin-6 released from fibroblasts is essential for up-regulation of matrix metalloproteinase-1 expression by U937 macrophages in coculture: cross-talking between fibroblasts and U937 macrophages exposed to high glucose.Effect of systemic tetracycline on the degradation of tetracycline-impregnated bilayered collagen membranes: an animal study.Inhibition of matrix metalloproteinase-9 activity by doxycycline ameliorates RANK ligand-induced osteoclast differentiation in vitro and in vivo.An in vitro study of plasticized poly(lactic-co-glycolic acid) films as possible guided tissue regeneration membranes: material properties and drug release kinetics.A combination of a chemically modified doxycycline and a bisphosphonate synergistically inhibits endotoxin-induced periodontal breakdown in rats.Inhibition of matrix metalloproteinase-mediated periodontal bone loss in rats: a comparison of 6 chemically modified tetracyclines.Effect of minocycline on healing of replanted dog teeth after extended dry times.The "cyclic" regimen of low-dose doxycycline for adult periodontitis: a preliminary study.Systemic tetracycline delays degradation of three different collagen membranes in rat calvaria.Healing of dehiscence defects following root surface demineralization with tetracycline: a histologic study in monkeys.Anti-inflammatory properties of doxycycline and minocycline in experimental models: an in vivo and in vitro comparative study.Evaluation of the inhibitory effect of triphala on PMN-type matrix metalloproteinase (MMP-9).Minocycline impairment of both osteoid tissue removal and osteoclastic resorption in a synchronized model of remodeling in the rat.Effects of Tetracyclines on Bone Metabolism
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P2860
Blocking periodontal disease progression by inhibiting tissue-destructive enzymes: a potential therapeutic role for tetracyclines and their chemically-modified analogs.
description
1993 nî lūn-bûn
@nan
1993年の論文
@ja
1993年論文
@yue
1993年論文
@zh-hant
1993年論文
@zh-hk
1993年論文
@zh-mo
1993年論文
@zh-tw
1993年论文
@wuu
1993年论文
@zh
1993年论文
@zh-cn
name
Blocking Periodontal Disease P ...... r Chemically-Modified Analogs.
@nl
Blocking periodontal disease p ...... r chemically-modified analogs.
@en
type
label
Blocking Periodontal Disease P ...... r Chemically-Modified Analogs.
@nl
Blocking periodontal disease p ...... r chemically-modified analogs.
@en
altLabel
Blocking Periodontal Disease P ...... r Chemically-Modified Analogs.
@en
prefLabel
Blocking Periodontal Disease P ...... r Chemically-Modified Analogs.
@nl
Blocking periodontal disease p ...... r chemically-modified analogs.
@en
P2860
P1476
Blocking Periodontal Disease P ...... ir Chemically-Modified Analogs
@en
P2093
Barry R Rifkin
Lorne M Golub
P2860
P304
P356
10.1902/JOP.1993.64.8S.819
P407
P433
P478
64 Suppl 8S
P577
1993-08-01T00:00:00Z