La autoantigen is cleaved in the COOH terminus and loses the nuclear localization signal during apoptosis.
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CK2 is responsible for phosphorylation of human La protein serine-366 and can modulate rpL37 5'-terminal oligopyrimidine mRNA metabolismSS-56, a novel cellular target of autoantibody responses in Sjögren syndrome and systemic lupus erythematosusScapinin, a putative protein phosphatase-1 regulatory subunit associated with the nuclear nonchromatin structureLa protein and its associated small nuclear and nucleolar precursor RNAsChemotherapy synergizes with radioimmunotherapy targeting La autoantigen in tumorsAtLa1 protein initiates IRES-dependent translation of WUSCHEL mRNA and regulates the stem cell homeostasis of Arabidopsis in response to environmental hazards.APOMAB, a La-specific monoclonal antibody, detects the apoptotic tumor response to life-prolonging and DNA-damaging chemotherapy.Sla1, a Schizosaccharomyces pombe homolog of the human La protein, induces ectopic meiosis when its C terminus is truncated.Altered autoantigen structure in Sjögren's syndrome: implications for the pathogenesis of autoimmune tissue damage.Initiation factor modifications in the preapoptotic phase.Ro60 requires Y3 RNA for cell surface exposure and inflammation associated with cardiac manifestations of neonatal lupusThe La antigen is over-expressed in lung cancer and is a selective dead cancer cell target for radioimmunotherapy using the La-specific antibody APOMAB®.Nonphosphorylated human La antigen interacts with nucleolin at nucleolar sites involved in rRNA biogenesis.Non-cytotoxic antiviral activities of granzymes in the context of the immune antiviral state.The labyrinth of interactions of Epstein-Barr virus-encoded small RNAs.Hydrogen peroxide induces La cytoplasmic shuttling and increases hepatitis C virus internal ribosome entry site-dependent translation.La autoantigen enhances translation of BiP mRNACleavage of La protein by granzyme H induces cytoplasmic translocation and interferes with La-mediated HCV-IRES translational activity.Detection of apoptosis-specific autoantibodies directed against granzyme B-induced cleavage fragments of the SS-B (La) autoantigen in sera from patients with primary Sjögren's syndrome.An optical probe for detecting chondrocyte apoptosis in response to mechanical injury.PDGF enhances IRES-mediated translation of Laminin B1 by cytoplasmic accumulation of La during epithelial to mesenchymal transition.Expression of lamins depends on epidermal differentiation and transformation.A bona fide La protein is required for embryogenesis in Arabidopsis thaliana.Caspase-mediated cleavage of the exosome subunit PM/Scl-75 during apoptosisLa Deletion from Mouse Brain Alters Pre-tRNA Metabolism and Accumulation of Pre-5.8S rRNA, with Neuron Death and Reactive Astrocytosis.Association of autoantibodies to nuclear lamin B1 with thromboprotection in systemic lupus erythematosus: lack of evidence for a direct role of lamin B1 in apoptotic blebs.Anti-ribonucleoproteins autoantibodies in patients with systemic autoimmune diseases. Relation with cutaneous photosensitivity.The La Motif and the RNA Recognition Motifs of Human La Autoantigen Contribute Individually to RNA Recognition and Subcellular Localization
P2860
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P2860
La autoantigen is cleaved in the COOH terminus and loses the nuclear localization signal during apoptosis.
description
2000 nî lūn-bûn
@nan
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
2000年论文
@zh
2000年论文
@zh-cn
name
La autoantigen is cleaved in t ...... ation signal during apoptosis.
@en
type
label
La autoantigen is cleaved in t ...... ation signal during apoptosis.
@en
prefLabel
La autoantigen is cleaved in t ...... ation signal during apoptosis.
@en
P2093
P2860
P356
P1476
La autoantigen is cleaved in t ...... ation signal during apoptosis.
@en
P2093
Hashimoto S
Masumoto J
Sarvotham H
Taniguchi S
P2860
P304
34465-34470
P356
10.1074/JBC.M003673200
P407
P577
2000-11-01T00:00:00Z