SUMO-1 modification of Mdm2 prevents its self-ubiquitination and increases Mdm2 ability to ubiquitinate p53.
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Stabilization and activation of p53 by the coactivator protein TAFII31Characterization of fortilin, a novel antiapoptotic proteinSmall ubiquitin-related modifier-1 modification regulates all-trans-retinoic acid-induced differentiation via stabilization of retinoic acid receptor αCUE domain containing 2 regulates degradation of progesterone receptor by ubiquitin-proteasomeThe tumour suppressor RASSF1A regulates mitosis by inhibiting the APC-Cdc20 complexKaposi's sarcoma-associated herpesvirus viral interferon regulatory factor 4 targets MDM2 to deregulate the p53 tumor suppressor pathwayMapping residues of SUMO precursors essential in differential maturation by SUMO-specific protease, SENP1Proteasome-independent disruption of PML oncogenic domains (PODs), but not covalent modification by SUMO-1, is required for human cytomegalovirus immediate-early protein IE1 to inhibit PML-mediated transcriptional repression.Desumoylation activity of Axam, a novel Axin-binding protein, is involved in downregulation of beta-catenin.Keap1 is a redox-regulated substrate adaptor protein for a Cul3-dependent ubiquitin ligase complex.A TSG101/MDM2 regulatory loop modulates MDM2 degradation and MDM2/p53 feedback controlUbiquitin-protein ligase activity of X-linked inhibitor of apoptosis protein promotes proteasomal degradation of caspase-3 and enhances its anti-apoptotic effect in Fas-induced cell deathThe checkpoint protein Chfr is a ligase that ubiquitinates Plk1 and inhibits Cdc2 at the G2 to M transition.Histone sumoylation is associated with transcriptional repressionCrystal structure of the SENP1 mutant C603S-SUMO complex reveals the hydrolytic mechanism of SUMO-specific proteaseRole of desumoylation in the development of prostate cancerMolecular profile of synovial fibroblasts in rheumatoid arthritis depends on the stage of proliferation.Hydrogen peroxide sensing, signaling and regulation of transcription factorsLessons learned from next-generation sequencing in head and neck cancerStructure characterization of the 26S proteasome.Sumoylation of MITF and its related family members TFE3 and TFEBCovalent modification of p73alpha by SUMO-1. Two-hybrid screening with p73 identifies novel SUMO-1-interacting proteins and a SUMO-1 interaction motifMDMX stability is regulated by p53-induced caspase cleavage in NIH3T3 mouse fibroblastsPIAS1-mediated sumoylation of focal adhesion kinase activates its autophosphorylationSumo-1 modification regulates the DNA binding activity of heat shock transcription factor 2, a promyelocytic leukemia nuclear body associated transcription factorSumoylation of Mdm2 by protein inhibitor of activated STAT (PIAS) and RanBP2 enzymesIn vitro ubiquitination of cyclin D1 by ROC1-CUL1 and ROC1-CUL3A RING finger protein Praja1 regulates Dlx5-dependent transcription through its ubiquitin ligase activity for the Dlx/Msx-interacting MAGE/Necdin family protein, Dlxin-1Ubc9 is a novel modulator of the induction properties of glucocorticoid receptorsSUMO-1 controls the protein stability and the biological function of phosducinPhosphorylation of murine double minute clone 2 (MDM2) protein at serine-267 by protein kinase CK2 in vitro and in cultured cellsATM-dependent phosphorylation of Mdm2 on serine 395: role in p53 activation by DNA damageTransport into and out of the nucleus.Distinct cysteine residues in Keap1 are required for Keap1-dependent ubiquitination of Nrf2 and for stabilization of Nrf2 by chemopreventive agents and oxidative stressSumoylation of Kif18A plays a role in regulating mitotic progressionFunctional interaction between human herpesvirus 6 immediate-early 2 protein and ubiquitin-conjugating enzyme 9 in the absence of sumoylation.Covalent modification of human immunodeficiency virus type 1 p6 by SUMO-1.Differential regulation of the two transcriptional activation domains of the coiled-coil coactivator CoCoA by sumoylation.RUNX family members are covalently modified and regulated by PIAS1-mediated sumoylationA combined epigenetic and non-genetic approach for reprogramming human somatic cells
P2860
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P2860
SUMO-1 modification of Mdm2 prevents its self-ubiquitination and increases Mdm2 ability to ubiquitinate p53.
description
2000 nî lūn-bûn
@nan
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
2000年论文
@zh
2000年论文
@zh-cn
name
SUMO-1 modification of Mdm2 pr ...... 2 ability to ubiquitinate p53.
@en
type
label
SUMO-1 modification of Mdm2 pr ...... 2 ability to ubiquitinate p53.
@en
prefLabel
SUMO-1 modification of Mdm2 pr ...... 2 ability to ubiquitinate p53.
@en
P2093
P1433
P1476
SUMO-1 modification of Mdm2 pr ...... 2 ability to ubiquitinate p53.
@en
P2093
P304
P356
10.1016/S0092-8674(00)80887-9
P407
P577
2000-06-01T00:00:00Z