A novel transcription factor, OB2-1, is required for overexpression of the proto-oncogene c-erbB-2 in mammary tumour lines.
about
Transcription factor AP-2alpha is preferentially cleaved by caspase 6 and degraded by proteasome during tumor necrosis factor alpha-induced apoptosis in breast cancer cellsUpdate on HER-2 as a target for cancer therapy: the ERBB2 promoter and its exploitation for cancer treatmentCoactivator PC4 mediates AP-2 transcriptional activity and suppresses ras-induced transformation dependent on AP-2 transcriptional interference.Comparative and functional analysis of the AP2 promoter indicates that conserved octamer and initiator elements are critical for activity.Derepression of the Her-2 uORF is mediated by a novel post-transcriptional control mechanism in cancer cellsThe developmentally regulated transcription factor AP-2 is involved in c-erbB-2 overexpression in human mammary carcinoma.HER-2 Evaluation in a Specific Gastric Cancer Population with the Highest Rate of Mortality in Spain.Alternative TFAP2A isoforms have distinct activities in breast cancerType 1 receptor tyrosine kinases are differentially phosphorylated in mammary carcinoma and differentially associated with steroid receptors.Critical determination of the frequency of c-erbB-2 amplification in breast cancer.c-erbB-4 protein expression in human breast cancerThe combined immunodetection of AP-2alpha and YY1 transcription factors is associated with ERBB2 gene overexpression in primary breast tumorsDifferent mechanisms are implicated in ERBB2 gene overexpression in breast and in other cancersIdentification of HTF (HER2 transcription factor) as an AP-2 (activator protein-2) transcription factor and contribution of the HTF binding site to ERBB2 gene overexpression.Targeting gene transcription: a new strategy to down-regulate c-erbB-2 expression in mammary carcinomaOestrogen and epidermal growth factor down-regulate erbB-2 oncogene protein expression in breast cancer cells by different mechanisms.Conjugated linoleic acid (CLA) inhibits expression of the Spot 14 (THRSP) and fatty acid synthase genes and impairs the growth of human breast cancer and liposarcoma cells.
P2860
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P2860
A novel transcription factor, OB2-1, is required for overexpression of the proto-oncogene c-erbB-2 in mammary tumour lines.
description
1993 nî lūn-bûn
@nan
1993年の論文
@ja
1993年学术文章
@wuu
1993年学术文章
@zh-cn
1993年学术文章
@zh-hans
1993年学术文章
@zh-my
1993年学术文章
@zh-sg
1993年學術文章
@yue
1993年學術文章
@zh
1993年學術文章
@zh-hant
name
A novel transcription factor, ...... rbB-2 in mammary tumour lines.
@en
type
label
A novel transcription factor, ...... rbB-2 in mammary tumour lines.
@en
prefLabel
A novel transcription factor, ...... rbB-2 in mammary tumour lines.
@en
P2860
P1433
P1476
A novel transcription factor, ...... rbB-2 in mammary tumour lines.
@en
P2093
Hollywood DP
P2860
P304
P407
P577
1993-06-01T00:00:00Z