Lipidation of apolipoprotein E influences its isoform-specific interaction with Alzheimer's amyloid beta peptides - Wikidata - wikimedia - TriplyDB

Lipidation of apolipoprotein E influences its isoform-specific interaction with Alzheimer's amyloid beta peptides

Lipidation of apolipoprotein E influences its isoform-specific interaction with Alzheimer's amyloid beta peptides

http://www.wikidata.org/entity/Q40879124

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Interactions of metals and Apolipoprotein E in Alzheimer's disease The generation and function of soluble apoE receptors in the CNS Cholesterol, APOE genotype, and Alzheimer disease: an epidemiologic study of Nigerian Yoruba Impact of apolipoprotein E on Alzheimer's disease ApoE promotes the proteolytic degradation of Abeta Role of apolipoprotein E in neurodegenerative diseases Apolipoprotein E and apolipoprotein E receptors: normal biology and roles in Alzheimer disease Tau-associated neuropathology in ganglion cell tumours increases with patient age but appears unrelated to ApoE genotype Reelin and apoE actions on signal transduction, synaptic function and memory formation Apolipoprotein E: isoform specific differences in tertiary structure and interaction with amyloid-β in human Alzheimer brain Preferential interactions between ApoE-containing lipoproteins and Aβ revealed by a detection method that combines size exclusion chromatography with non-reducing gel-shift Low-density lipoprotein receptor represents an apolipoprotein E-independent pathway of Aβ uptake and degradation by astrocytes Effect of apolipoprotein E genotype and diet on apolipoprotein E lipidation and amyloid peptides: randomized clinical trial Apolipoprotein E-low density lipoprotein receptor interaction affects spatial memory retention and brain ApoE levels in an isoform-dependent manner.Apolipoprotein-E forms dimers in human frontal cortex and hippocampus Effects of medicinal plants on Alzheimer's disease and memory deficits.Apolipoprotein E - A Multifunctional Protein with Implications in Various Pathologies as a Result of Its Structural Features The potential applications of Apolipoprotein E in personalized medicine Clearance of Alzheimer's amyloid-ss(1-40) peptide from brain by LDL receptor-related protein-1 at the blood-brain barrier Should the ApoE genotype be a covariate for clinical trials in Alzheimer disease?Confounding factors influencing amyloid Beta concentration in cerebrospinal fluid A multifaceted role for apoE in the clearance of beta-amyloid across the blood-brain barrier.SUCLG2 identified as both a determinator of CSF Aβ1-42 levels and an attenuator of cognitive decline in Alzheimer's disease.Apolipoprotein E ε2 genotype delays onset of dementia with Lewy bodies in a Norwegian cohort A differential association of Apolipoprotein E isoforms with the amyloid-β oligomer in solution.Apolipoprotein E: from lipid transport to neurobiology More than cholesterol transporters: lipoprotein receptors in CNS function and neurodegeneration The role of apolipoprotein E in Alzheimer's disease.Clearance of amyloid-beta peptide across the blood-brain barrier: implication for therapies in Alzheimer's disease.Elevation in sphingomyelin synthase activity is associated with increases in amyloid-beta peptide generation.A synthetic peptide blocking the apolipoprotein E/beta-amyloid binding mitigates beta-amyloid toxicity and fibril formation in vitro and reduces beta-amyloid plaques in transgenic mice.Atherosclerosis and Alzheimer--diseases with a common cause? Inflammation, oxysterols, vasculature Extracellular proteolysis of apolipoprotein E (apoE) by secreted serine neuronal protease Human apoE isoforms differentially regulate brain amyloid-β peptide clearance High density lipoprotein structure-function and role in reverse cholesterol transport.Association of ApoE and LRP mRNA levels with dementia and AD neuropathology.Apolipoprotein E promotes β-amyloid trafficking and degradation by modulating microglial cholesterol levels.Overexpression of ABCA1 reduces amyloid deposition in the PDAPP mouse model of Alzheimer disease.Role of ABC transporters in the pathogenesis of Alzheimer's disease ApoE4 upregulates the activity of mitochondria-associated ER membranes.

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P2860

Lipidation of apolipoprotein E influences its isoform-specific interaction with Alzheimer's amyloid beta peptides

http://www.wikidata.org/entity/Q40879124

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2000 nî lūn-bûn

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2000年の論文

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2000年学术文章

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2000年学术文章

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2000年学术文章

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2000年学术文章

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2000年学术文章

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2000年學術文章

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2000年學術文章

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2000年學術文章

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name

Lipidation of apolipoprotein E ...... heimer's amyloid beta peptides

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Lipidation of apolipoprotein E ...... heimer's amyloid beta peptides

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Lipidation of apolipoprotein E ...... Alzheimer’s amyloid β peptides

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Lipidation of apolipoprotein E ...... heimer's amyloid beta peptides

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0264-6021:3480359

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Biochemical Journal

P1476

Lipidation of apolipoprotein E ...... heimer's amyloid beta peptides

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P2093

A Kumar

http://www.w3.org/2001/XMLSchema#string

A Rostagno

http://www.w3.org/2001/XMLSchema#string

B Frangione

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B Permanne

http://www.w3.org/2001/XMLSchema#string

B Zlokovic

http://www.w3.org/2001/XMLSchema#string

E Matsubara

http://www.w3.org/2001/XMLSchema#string

J D Smith

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J Ghiso

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M J Ladu

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R Vidal

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P2860

Apolipoprotein E: high-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease

Behavior of human apolipoprotein E in aqueous solutions and at interfaces

Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families

Apolipoprotein E: a pathological chaperone protein in patients with cerebral and systemic amyloid

Isoform-specific binding of apolipoprotein E to beta-amyloid

Association of human, rat, and rabbit apolipoprotein E with beta-amyloid

Diffusible, nonfibrillar ligands derived from Abeta1-42 are potent central nervous system neurotoxins

Association of apolipoprotein E allele epsilon 4 with late-onset familial and sporadic Alzheimer's disease

Isolation and quantification of soluble Alzheimer's beta-peptide from biological fluids.

Binding of human apolipoprotein E to synthetic amyloid beta peptide: isoform-specific effects and implications for late-onset Alzheimer disease.

P304

359-365

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10.1042/0264-6021:3480359

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10.1042/BJ3480359

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2

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P478

348 Pt 2

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247449720

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10816430

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Alzheimer's disease

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1221074

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