Distinct mechanisms of STAT phosphorylation via the interferon-alpha/beta receptor. Selective inhibition of STAT3 and STAT5 by piceatannol.
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Piceatannol, natural polyphenolic stilbene, inhibits adipogenesis via modulation of mitotic clonal expansion and insulin receptor-dependent insulin signaling in early phase of differentiationCutting edge: selective tyrosine dephosphorylation of interferon-activated nuclear STAT5 by the VHR phosphatasePrevention of colitis-associated cancer: natural compounds that target the IL-6 soluble receptorSignal transducer and activator of transcription 3 (STAT3) regulates collagen-induced platelet aggregation independently of its transcription factor activity.Novel sequential ChIP and simplified basic ChIP protocols for promoter co-occupancy and target gene identification in human embryonic stem cells.Decreased expression of the Nkx2.8 gene correlates with tumor progression and a poor prognosis in HCC cancer.IFN priming is necessary but not sufficient to turn on a migratory dendritic cell program in lupus monocytes.Transcription factor BACH2 is transcriptionally regulated by the BCR/ABL oncogene.Inhibition of lipopolysaccharide-induced interferon regulatory factor 3 activation and protection from septic shock by hydroxystilbenes.STAT3 activation by type I interferons is dependent on specific tyrosines located in the cytoplasmic domain of interferon receptor chain 2c. Activation of multiple STATS proceeds through the redundant usage of two tyrosine residues.Latency type-dependent modulation of Epstein-Barr virus-encoded latent membrane protein 1 expression by type I interferons in B cells.STAT3, p38 MAPK, and NF-kappaB drive unopposed monocyte-dependent fibroblast MMP-1 secretion in tuberculosis.Multiplex SNP genotyping in pooled DNA samples by a four-colour microarray system.Tyrosine kinase inhibitors: Multi-targeted or single-targeted?Signal transducer and activator of transcription-3, inflammation, and cancer: how intimate is the relationship?.Enhanced phosphorylation of STAT-1 is dependent on double-stranded RNA-dependent protein kinase signaling in HLA-B27-expressing U937 monocytic cells.Vpr cytopathicity independent of G2/M cell cycle arrest in human immunodeficiency virus type 1-infected CD4+ T cellsVirus Multiplicity of Infection Affects Type I Interferon Subtype Induction Profiles and Interferon-Stimulated GenesPhospho-proteomic immune analysis by flow cytometry: from mechanism to translational medicine at the single-cell level.The cancer preventative agent resveratrol is converted to the anticancer agent piceatannol by the cytochrome P450 enzyme CYP1B1.Expression of activated STAT5 in neoplastic mast cells in systemic mastocytosis: subcellular distribution and role of the transforming oncoprotein KIT D816V.Signal transducer and activator of transcription 3 (STAT3): a promising target for anticancer therapy.Protein kinase C-delta (PKC-delta ) is activated by type I interferons and mediates phosphorylation of Stat1 on serine 727.Factors involved in CLL pathogenesis and cell survival are disrupted by differentiation of CLL B-cells into antibody-secreting cells.Natural Nuclear Factor Kappa Beta Inhibitors: Safe Therapeutic Options for Inflammatory Bowel Disease.Multifaceted ability of naturally occurring polyphenols against metastatic cancer.Phosphorylated STAT3 physically interacts with NPM and transcriptionally enhances its expression in cancer.Trimethoxy-resveratrol and piceatannol administered orally suppress and inhibit tumor formation and growth in prostate cancer xenografts.Epidermal growth factor receptor signaling impairs the antiviral activity of interferon-alpha.The Therapeutic Potential of Piceatannol, a Natural Stilbene, in Metabolic Diseases: A Review.Piceatannol inhibits phorbol ester-induced NF-kappa B activation and COX-2 expression in cultured human mammary epithelial cells.Genomic and expression profiling identifies the B-cell associated tyrosine kinase Syk as a possible therapeutic target in mantle cell lymphoma.TEL-Syk fusion constitutively activates PI3-K/Akt, MAPK and JAK2-independent STAT5 signal pathways.Lack of requirement of STAT1 for activation of nuclear factor-kappaB, c-Jun NH2-terminal protein kinase, and apoptosis by tumor necrosis factor-alpha.Production of highly bioactive resveratrol analogues pterostilbene and piceatannol in metabolically engineered grapevine cell culturesAggregated IgG inhibits the differentiation of human fibrocytes.Identification of oncostatin M as a STAT5-dependent mediator of bone marrow remodeling in KIT D816V-positive systemic mastocytosisCross talk of the interferon-alpha/beta signalling complex with gp130 for effective interleukin-6 signalling.Oncostatin M causes VEGF release from human airway smooth muscle: synergy with IL-1beta.The PGE2-Stat3 interaction in doxorubicin-induced myocardial apoptosis.
P2860
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P2860
Distinct mechanisms of STAT phosphorylation via the interferon-alpha/beta receptor. Selective inhibition of STAT3 and STAT5 by piceatannol.
description
2000 nî lūn-bûn
@nan
2000年の論文
@ja
2000年学术文章
@wuu
2000年学术文章
@zh-cn
2000年学术文章
@zh-hans
2000年学术文章
@zh-my
2000年学术文章
@zh-sg
2000年學術文章
@yue
2000年學術文章
@zh
2000年學術文章
@zh-hant
name
Distinct mechanisms of STAT ph ...... TAT3 and STAT5 by piceatannol.
@en
type
label
Distinct mechanisms of STAT ph ...... TAT3 and STAT5 by piceatannol.
@en
prefLabel
Distinct mechanisms of STAT ph ...... TAT3 and STAT5 by piceatannol.
@en
P356
P1476
Distinct mechanisms of STAT ph ...... TAT3 and STAT5 by piceatannol.
@en
P304
12661-12666
P356
10.1074/JBC.275.17.12661
P407
P577
2000-04-01T00:00:00Z