HTLV-1 tax oncoprotein represses the p53-mediated trans-activation function through coactivator CBP sequestration.
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SIK1 couples LKB1 to p53-dependent anoikis and suppresses metastasisAMF1 (GPS2) modulates p53 transactivationMapping the interactions of the p53 transactivation domain with the KIX domain of CBPModulation of retinoid signaling by a cytoplasmic viral protein via sequestration of Sp110b, a potent transcriptional corepressor of retinoic acid receptor, from the nucleusCoactivators p300 and PCAF physically and functionally interact with the foamy viral trans-activatorRole of Tax protein in human T-cell leukemia virus type-I leukemogenicityHuman T-cell leukemia virus type I (HTLV-I) infection and the onset of adult T-cell leukemia (ATL)The HTLV-1 Tax protein binding domain of cyclin-dependent kinase 4 (CDK4) includes the regulatory PSTAIRE helixNew insights into the role of nuclear factor-kB in cell growth regulationMolecular Studies of HTLV-1 Replication: An UpdateModes of Human T Cell Leukemia Virus Type 1 Transmission, Replication and PersistenceInteraction of retroviral Tax oncoproteins with tristetraprolin and regulation of tumor necrosis factor-alpha expressionp53 Transcriptional activity is mediated through the SRC1-interacting domain of CBP/p300Tax-1 and Tax-2 similarities and differences: focus on post-translational modifications and NF-κB activation.Molecular biology and pathogenesis of the human T-cell leukaemia/lymphotropic virus Type-1 (HTLV-1).A novel one-class SVM based negative data sampling method for reconstructing proteome-wide HTLV-human protein interaction networks.Comparison of the seleno-transcriptome expression between human non-cancerous mammary epithelial cells and two human breast cancer cell linesAcetylation of the human T-cell leukemia virus type 1 Tax oncoprotein by p300 promotes activation of the NF-kappaB pathway.Genetic evidence of a role for ATM in functional interaction between human T-cell leukemia virus type 1 Tax and p53.Kaposi's sarcoma-associated herpesvirus open reading frame 50 represses p53-induced transcriptional activity and apoptosis.Human T-lymphotropic virus type 1 p30(II) regulates gene transcription by binding CREB binding protein/p300.CREB/ATF-dependent repression of cyclin a by human T-cell leukemia virus type 1 Tax protein.Evidence for NF-kappaB- and CBP-independent repression of p53's transcriptional activity by human T-cell leukemia virus type 1 Tax in mouse embryo and primary human fibroblasts.The oncoprotein Tax binds the SRC-1-interacting domain of CBP/p300 to mediate transcriptional activation.EWS-ATF-1 chimeric protein in soft tissue clear cell sarcoma associates with CREB-binding protein and interferes with p53-mediated trans-activation function.The DNA damage response in viral-induced cellular transformationEnhanced activation of tax-dependent transcription of human T-cell leukemia virus type I (HTLV-I) long terminal repeat by TORC3.Histone acetyltransferase (HAT) activity of p300 modulates human T lymphotropic virus type 1 p30II-mediated repression of LTR transcriptional activity.The human T-cell lymphoma/leukemia viruses.Human T Lymphotropic Virus Type 1 (HTLV-1): Molecular Biology and Oncogenesis.Evidence for cooperative transforming activity of the human pituitary tumor transforming gene and human T-cell leukemia virus type 1 Tax.Negative regulation of the SH2-homology containing protein-tyrosine phosphatase-1 (SHP-1) P2 promoter by the HTLV-1 Tax oncoproteinHuman T-cell leukemia virus type 1 (HTLV-1) and leukemic transformation: viral infectivity, Tax, HBZ and therapy.Wip1 and p53 contribute to HTLV-1 Tax-induced tumorigenesisHuman T-cell leukemia virus type-1-encoded protein HBZ represses p53 function by inhibiting the acetyltransferase activity of p300/CBP and HBO1.Human T-cell leukemia virus type 1 (HTLV-1) and HTLV-2 tax oncoproteins modulate cell cycle progression and apoptosis.Human T-lymphotropic virus proteins and post-translational modification pathwaysDevelopment of ultra-super sensitive immunohistochemistry and its application to the etiological study of adult T-cell leukemia/lymphoma.p53 modulates the activity of the GLI1 oncogene through interactions with the shared coactivator TAF9.Interferon-α (IFN-α) suppresses HTLV-1 gene expression and cell cycling, while IFN-α combined with zidovudine induces p53 signaling and apoptosis in HTLV-1-infected cells
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P2860
HTLV-1 tax oncoprotein represses the p53-mediated trans-activation function through coactivator CBP sequestration.
description
2000 nî lūn-bûn
@nan
2000年の論文
@ja
2000年学术文章
@wuu
2000年学术文章
@zh-cn
2000年学术文章
@zh-hans
2000年学术文章
@zh-my
2000年学术文章
@zh-sg
2000年學術文章
@yue
2000年學術文章
@zh
2000年學術文章
@zh-hant
name
HTLV-1 tax oncoprotein repress ...... coactivator CBP sequestration.
@en
type
label
HTLV-1 tax oncoprotein repress ...... coactivator CBP sequestration.
@en
prefLabel
HTLV-1 tax oncoprotein repress ...... coactivator CBP sequestration.
@en
P2093
P2860
P356
P1433
P1476
HTLV-1 tax oncoprotein repress ...... coactivator CBP sequestration.
@en
P2093
K Shimotohno
P2860
P2888
P304
P356
10.1038/SJ.ONC.1203450
P407
P577
2000-03-01T00:00:00Z
P5875
P6179
1023764400