Polymorphism of the cytochrome P450 CYP2D6 gene in a European population: characterization of 48 mutations and 53 alleles, their frequencies and evolution.
about
Expression and functional analysis of CYP2D6.24, CYP2D6.26, CYP2D6.27, and CYP2D7 isozymesA new therapeutic option for postoperative pain management with oxycodone HCI injectionPharmacogenomics of Drug Metabolizing Enzymes and Transporters: Relevance to Precision MedicineInfluence of phenylalanine-481 substitutions on the catalytic activity of cytochrome P450 2D6Causes of genome instability: the effect of low dose chemical exposures in modern societyIdentification of new alleles and the determination of alleles and genotypes frequencies at the CYP2D6 gene in EmiratisMolecular dynamics of CYP2D6 polymorphisms in the absence and presence of a mechanism-based inactivator reveals changes in local flexibility and dominant substrate access channelsWASP: a Web-based Allele-Specific PCR assay designing tool for detecting SNPs and mutations.In vitro metabolism of exemestane by hepatic cytochrome P450s: impact of nonsynonymous polymorphisms on formation of the active metabolite 17β-dihydroexemestaneCytochrome P450-2D6 extensive metabolizers are more vulnerable to methamphetamine-associated neurocognitive impairment: preliminary findings.Anandamide oxidation by wild-type and polymorphically expressed CYP2B6 and CYP2D6.CYP2D6 polymorphisms in patients with porphyriasPharmacogenetics and gender association with psychotic episodes on nortriptyline lower doses: patient cases.A discordance between cytochrome P450 2D6 genotype and phenotype in patients undergoing methadone maintenance treatment.mRNA transcript diversity creates new opportunities for pharmacological intervention.Allelic and genotype frequencies of catechol-O-methyltransferase (Val158Met) and CYP2D6*10 (Pro34Ser) single nucleotide polymorphisms in the Philippines.Influence of hydroxychloroquine on the bioavailability of oral metoprololGenetics and psychopharmacology: prospects for individualized treatment.CYP2D7 Sequence Variation Interferes with TaqMan CYP2D6 (*) 15 and (*) 35 Genotyping.Novel cytochrome P450-2D6 promoter sequence variations in hepatitis C positive and negative subjects.Evaluation of a [13C]-dextromethorphan breath test to assess CYP2D6 phenotype.Influence of CYP2D6 polymorphisms on serum levels of tamoxifen metabolites in Spanish women with breast cancerMolecular mechanisms of statin intolerancePopulation pharmacokinetic/pharmacodynamic modelling of the effects of axomadol and its O-demethyl metabolite on pupil diameter and nociception in healthy subjectsMetabolic capacity of CYP2D6 within an Iranian population (Mazandaran Province).Factors affecting the development of adverse drug reactions to β-blockers in hospitalized cardiac patient populationCorrelation of CpG Island Methylation of the Cytochrome P450 2E1/2D6 Genes with Liver Injury Induced by Anti-Tuberculosis Drugs: A Nested Case-Control Study.Perioperative genomic profiles using structure-specific oligonucleotide probes.Cytochrome P450 2D6.Pharmacogenetics in American Indian populations: analysis of CYP2D6, CYP3A4, CYP3A5, and CYP2C9 in the Confederated Salish and Kootenai Tribes.Sequencing the CYP2D6 gene: from variant allele discovery to clinical pharmacogenetic testing.Relationship between cytochrome P450 polymorphisms and prescribed medication in elderly haemodialysis patients.Genetic variants in the cytochrome P450 2D6 gene in the Sri Lankan population.Human pharmacogenomics: the development of a science.CYP2D6 genotyping as an alternative to phenotyping for determination of metabolic status in a clinical trial setting.Response to serotonin reuptake inhibitors in OCD is not influenced by common CYP2D6 polymorphisms.A convenient five-drug cocktail for the assessment of major drug metabolizing enzymes: a pilot study.Pharmacoresistant Severe Mental Health Disorders in Children and Adolescents: Functional Abnormalities of Cytochrome P450 2D6.Good genes, oxidative stress and condition-dependent sexual signals.CYP2D6 genotype can help to predict effectiveness and safety during opioid treatment for chronic low back pain: results from a retrospective study in an Italian cohort
P2860
Q24320062-BCB58CD1-F28A-49ED-BF36-EAD1AA2C64ACQ26747676-28957F71-9FEF-4634-9784-9270B22AA836Q27692687-57574798-C168-4D45-A0FD-AC9A3A730C55Q28361814-F25B4F94-BF41-4B92-BB98-A590DB35BA49Q28388277-83C4E5A2-39E8-4F4C-A91B-965901C11585Q28478547-498C36F5-61BE-4B27-9063-7C5177F3523BQ28543572-F2548C44-0526-4F8E-91B0-65E778E66BB4Q33294098-0CAF1D36-8FCD-4506-97EB-A219936E98D7Q33777963-BC7A06D8-7F51-42C0-863C-0A4721C14CB5Q34132390-CC0B49B3-0E7F-47EA-8933-58C939B5F384Q34856974-B5663211-055F-4ACE-B3C9-C3DCA1EFCF97Q35586929-CF4ECF96-E619-4FCF-90E5-24F5ED92E97EQ35687771-5B248716-1197-4312-81F8-FADDCB25255CQ35825489-CA9E7F9B-79A9-45EB-8F32-7A791F9AC5AFQ35913120-3514FE5E-AC86-465F-83AF-616A041A0900Q36038272-12046D9F-2659-4059-889A-8CB95053AA06Q36055442-D118F7DB-5618-467D-93EC-12A852832184Q36206096-B38C5B2A-F451-4FF3-8682-669E4A5873D0Q36454174-D9915F8E-CD86-49C5-9029-E4759349CE88Q36551234-1024A6E3-F90D-4997-A4B6-CE56DB32CC41Q36684887-E77A49CB-2A4C-402E-9EA9-ED25D0068483Q36909858-56470AA4-FCCF-4CC9-B94F-62E6B7B0180DQ36958324-FD19185C-992B-4D0E-916C-B7DC909B11FEQ37030723-0B16CE36-1283-47FD-9B27-D5B9CA5443E6Q37155795-AB8BF595-1D58-4182-84D0-6E55F0779820Q37158873-797BEF3E-C404-48BF-9E6C-63FD0A0965CDQ37202900-C451E564-6711-43E9-91CF-0CA70BAB669FQ37376199-6C459EFD-2AFC-4B6B-854B-6BEB442575AAQ37513508-31C97588-9AEC-463F-97E9-312D9A37D734Q37608121-A614D5F2-2A5C-4B93-B876-9BA9D787B82DQ39282325-8656C266-234E-4375-9845-FD71F8DE30B2Q39295178-9660615B-AD4F-480A-8BFA-D7F019562D0DQ41881718-0DE667F3-414F-47C5-8960-24D96EF42B7EQ41985354-257CB8BF-EFC0-46FC-899C-AD0461EADC80Q41987357-93CB9BDA-6623-463D-9BC0-A24528D494E5Q42134010-9E00AE90-7417-4142-94BD-0EBE3BA04D7DQ42284131-80C00E3A-60F0-45A1-8C20-ED964466DF7CQ50130078-AF10461B-4D89-4F5F-87A7-D47DD73B4521Q54102453-8053697C-A2D7-4627-AAB3-92C0D63A433DQ58698638-9439F020-005B-4E80-971B-ACF95DEF3652
P2860
Polymorphism of the cytochrome P450 CYP2D6 gene in a European population: characterization of 48 mutations and 53 alleles, their frequencies and evolution.
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年学术文章
@wuu
1997年学术文章
@zh-cn
1997年学术文章
@zh-hans
1997年学术文章
@zh-my
1997年学术文章
@zh-sg
1997年學術文章
@yue
1997年學術文章
@zh
1997年學術文章
@zh-hant
name
Polymorphism of the cytochrome ...... eir frequencies and evolution.
@en
type
label
Polymorphism of the cytochrome ...... eir frequencies and evolution.
@en
prefLabel
Polymorphism of the cytochrome ...... eir frequencies and evolution.
@en
P2093
P1476
Polymorphism of the cytochrome ...... heir frequencies and evolution
@en
P2093
J J Lafitte
J M Lo Guidice
P304
P356
10.1097/00008571-199706000-00004
P577
1997-06-01T00:00:00Z