The role of peptides in T cell alloreactivity is determined by self-major histocompatibility complex molecules.
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Crystal structure of a T cell receptor bound to an allogeneic MHC moleculeWhat Is Direct Allorecognition?The peptide-specific alloreactive human T cell repertoire varies largely between individuals and is not extended in HLA-A*0205--anti-HLA-A*0201 pairings.Alloreactivity: an old puzzle revisited.Thymic selection stifles TCR reactivity with the main chain structure of MHC and forces interactions with the peptide side chains.Alloreactivity is limited by the endogenous peptide repertoireInsights into the specificity and function of (allo)antigen-reactive T cells.Post-transplant renal tubulitis: the recruitment, differentiation and persistence of intra-epithelial T cells.Identities of P2 and P3 Residues of H-2Kb-Bound Peptides Determine Mouse Ly49C Recognition.On 'reactivity' versus 'tolerance'.MHC restriction and allogeneic immune responses.Concise review: immunologic lessons from solid organ transplantation for stem cell-based therapies.Endogenous-peptide-dependent alloreactivity: new scientific insights and clinical implications.A computational pipeline to generate MHC binding motifs.Individual MHCI-Restricted T-Cell Receptors are Characterized by a Unique Peptide Recognition Signature.Activation of a T cell hybridoma by an alloligand results in differential effects on IL-2 secretion and activation-induced cell death.Alloreactive T cells respond specifically to multiple distinct peptide-MHC complexes.A "hotspot" for autoimmune T cells in type 1 diabetes.A similarity in peptide cross-reactivity between alloantigen- and nominal antigen-induced CD8+ T cell responses in vitro.Reduced alloreactive T-cell activation after alcohol intake is due to impaired monocyte accessory cell function and correlates with elevated IL-10, IL-13, and decreased IFNgamma levels.Alloreactivity between disparate cognate and allogeneic pMHC-I complexes is the result of highly focused, peptide-dependent structural mimicry.Cytotoxic herpes simplex type 2-specific, DQ0602-restricted CD4 T+-cell clones show alloreactivity to DQ0601.Zinc in pharmacological doses suppresses allogeneic reaction without affecting the antigenic response.Myeloma-reactive allospecific cytotoxic T lymphocytes lyse target cells via the granule exocytosis pathway.
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P2860
The role of peptides in T cell alloreactivity is determined by self-major histocompatibility complex molecules.
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2000 nî lūn-bûn
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2000年学术文章
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The role of peptides in T cell ...... mpatibility complex molecules.
@en
type
label
The role of peptides in T cell ...... mpatibility complex molecules.
@en
prefLabel
The role of peptides in T cell ...... mpatibility complex molecules.
@en
P2093
P2860
P356
P1476
The role of peptides in T cell ...... mpatibility complex molecules.
@en
P2093
Netuschil N
Rammensee HG
Stevanović S
P2860
P304
P356
10.1084/JEM.191.5.805
P407
P577
2000-03-01T00:00:00Z