Structural determinants required for apical sorting of an intestinal brush-border membrane protein.
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Human meprin beta: O-linked glycans in the intervening region of the type I membrane protein protect the C-terminal region from proteolytic cleavage and diminish its secretionGalectin-4 and sulfatides in apical membrane trafficking in enterocyte-like cellsThe Diverse Forms of Lactose Intolerance and the Putative Linkage to Several CancersA glutamine to proline exchange at amino acid residue 1098 in sucrase causes a temperature-sensitive arrest of sucrase-isomaltase in the endoplasmic reticulum and cis-GolgiAltered folding, turnover, and polarized sorting act in concert to define a novel pathomechanism of congenital sucrase-isomaltase deficiencyCholesterol depletion reduces apical transport capacity in epithelial Madin-Darby canine kidney cellsAnnexin II is required for apical transport in polarized epithelial cells.Cytosolic COOH terminus of the peptide transporter PEPT2 is involved in apical membrane localization of the protein.Trafficking to the apical and basolateral membranes in polarized epithelial cellsMucin-like domain of enteropeptidase directs apical targeting in Madin-Darby canine kidney cells.Galectin-4-mediated transcytosis of transferrin receptor.Congenital sucrase-isomaltase deficiency arising from cleavage and secretion of a mutant form of the enzyme.Core-glycosylated mucin-like repeats from MUC1 are an apical targeting signalRole of N- and O-glycans in polarized biosynthetic sorting.The basolateral targeting signal of CD147 (EMMPRIN) consists of a single leucine and is not recognized by retinal pigment epithelium.Polarized traffic towards the cell surface: how to find the route.Apical trafficking in epithelial cells: signals, clusters and motors.Sucrase is an intramolecular chaperone located at the C-terminal end of the sucrase-isomaltase enzyme complex.Intestinal dipeptidyl peptidase IV is efficiently sorted to the apical membrane through the concerted action of N- and O-glycans as well as association with lipid microdomains.Characteristics and structural requirements of apical sorting of the rat growth hormone through the O-glycosylated stalk region of intestinal sucrase-isomaltase.Protocadherin of the liver, kidney, and colon associates with detergent-resistant membranes during cellular differentiation.Polarized apical sorting of guanylyl cyclase C is specified by a cytosolic signal.A novel type of detergent-resistant membranes may contribute to an early protein sorting event in epithelial cells.Apical transport and folding of prostate-specific membrane antigen occurs independent of glycan processing.Prohormone-convertase 1 processing enhances post-Golgi sorting of prothyrotropin-releasing hormone-derived peptides.Induction of a storage phenotype and abnormal intracellular localization of apical glycoproteins are two independent responses to GalNAcalpha-O-bn.Second cysteine-rich region of epidermal growth factor receptor contains targeting information for caveolae/rafts.Evolution of lutropin to chorionic gonadotropin generates a specific routing signal for apical release in vivo.Cytoplasmic signals mediate apical early endosomal targeting of endotubin in MDCK cells.Molecular basis of aberrant apical protein transport in an intestinal enzyme disorder.A point mutation in the juxtamembrane stalk of human angiotensin I-converting enzyme invokes the action of a distinct secretase.Long term differential consequences of miglustat therapy on intestinal disaccharidases.O-glycosylation of mucin-like domain retains the neutral ceramidase on the plasma membranes as a type II integral membrane protein.Characterization of Mucosal Disaccharidases from Human Intestine.Impact of glycosylation and detergent-resistant membranes on the function of intestinal sucrase-isomaltase.Cloning and characterization of the mammalian-specific nicolin 1 gene (NICN1) encoding a nuclear 24 kDa protein.
P2860
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P2860
Structural determinants required for apical sorting of an intestinal brush-border membrane protein.
description
2000 nî lūn-bûn
@nan
2000年の論文
@ja
2000年学术文章
@wuu
2000年学术文章
@zh-cn
2000年学术文章
@zh-hans
2000年学术文章
@zh-my
2000年学术文章
@zh-sg
2000年學術文章
@yue
2000年學術文章
@zh
2000年學術文章
@zh-hant
name
Structural determinants requir ...... brush-border membrane protein.
@en
type
label
Structural determinants requir ...... brush-border membrane protein.
@en
prefLabel
Structural determinants requir ...... brush-border membrane protein.
@en
P2093
P2860
P356
P1476
Structural determinants requir ...... brush-border membrane protein.
@en
P2093
P2860
P304
P356
10.1074/JBC.275.9.6566
P407
P577
2000-03-01T00:00:00Z