Sustained expression of human factor VIII in mice using a parvovirus-based vector.
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The gene therapy journey for hemophilia: are we there yet?Gene therapy for hemophiliaComparison of factor VIII transgenes bioengineered for improved expression in gene therapy of hemophilia ADirected engineering of a high-expression chimeric transgene as a strategy for gene therapy of hemophilia A.A limited number of transducible hepatocytes restricts a wide-range linear vector dose response in recombinant adeno-associated virus-mediated liver transductionInduction of immune tolerance to coagulation factor IX antigen by in vivo hepatic gene transfer.Protein replacement therapy and gene transfer in canine models of hemophilia A, hemophilia B, von willebrand disease, and factor VII deficiency.Persistent expression of factor VIII in vivo following nonprimate lentiviral gene transfer.Tolerance induction by viral in vivo gene transferEngineering Factor Viii for Hemophilia Gene Therapy.Therapeutic levels of FVIII following a single peripheral vein administration of rAAV vector encoding a novel human factor VIII variantTransient blockade of the inducible costimulator pathway generates long-term tolerance to factor VIII after nonviral gene transfer into hemophilia A miceEnhanced factor VIII heavy chain for gene therapy of hemophilia AImmunomodulation for inhibitors in hemophilia A: the important role of Treg cellsLiver-Directed Adeno-Associated Viral Gene Therapy for Hemophilia.Cross-packaging of a single adeno-associated virus (AAV) type 2 vector genome into multiple AAV serotypes enables transduction with broad specificity.Advances in Overcoming Immune Responses following Hemophilia Gene Therapy.
P2860
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P2860
Sustained expression of human factor VIII in mice using a parvovirus-based vector.
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2000 nî lūn-bûn
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Sustained expression of human factor VIII in mice using a parvovirus-based vector.
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type
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Sustained expression of human factor VIII in mice using a parvovirus-based vector.
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Sustained expression of human factor VIII in mice using a parvovirus-based vector.
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P2093
P1433
P1476
Sustained expression of human factor VIII in mice using a parvovirus-based vector
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P2093
P304
P407
P577
2000-03-01T00:00:00Z