MAPK pathways activate and phosphorylate the osteoblast-specific transcription factor, Cbfa1.
about
Distinct roles for mitogen-activated protein kinase phosphatase-1 (MKP-1) and ERK-MAPK in PTH1R signaling during osteoblast proliferation and differentiationProlyl isomerase Pin1 enhances osteoblast differentiation through Runx2 regulationTranscriptional regulation of osteoblastsThe p38 MAPK pathway is essential for skeletogenesis and bone homeostasis in miceRepression of Runx2 by androgen receptor (AR) in osteoblasts and prostate cancer cells: AR binds Runx2 and abrogates its recruitment to DNAGeneral transcription factor IIA-gamma increases osteoblast-specific osteocalcin gene expression via activating transcription factor 4 and runt-related transcription factor 2Differential effects of ERK and p38 signaling in BMP-2 stimulated hypertrophy of cultured chick sternal chondrocytesp38 MAPK Signaling in Osteoblast DifferentiationRole of RUNX2 in Breast CarcinogenesisAP-1 and Cbfa/runt physically interact and regulate parathyroid hormone-dependent MMP13 expression in osteoblasts through a new osteoblast-specific element 2/AP-1 composite elementTherapeutic treatments potentially mediated by melatonin receptors: potential clinical uses in the prevention of osteoporosis, cancer and as an adjuvant therapyPhosphophoryn regulates the gene expression and differentiation of NIH3T3, MC3T3-E1, and human mesenchymal stem cells via the integrin/MAPK signaling pathwayGain-of-function mutation in FGFR3 in mice leads to decreased bone mass by affecting both osteoblastogenesis and osteoclastogenesisHarmful effects of the azathioprine metabolite 6-mercaptopurine in vascular cells: induction of mineralizationExpression of osterix Is Regulated by FGF and Wnt/β-Catenin Signalling during Osteoblast DifferentiationThe protein kinase C pathway plays a central role in the fibroblast growth factor-stimulated expression and transactivation activity of Runx2Foxo1 mediates insulin-like growth factor 1 (IGF1)/insulin regulation of osteocalcin expression by antagonizing Runx2 in osteoblastsTranscriptional coactivation of bone-specific transcription factor Cbfa1 by TAZImprovement of the cell-loading efficiency of biomaterials by inoculation with stem cell-based microspheres, in osteogenesis.The roles of extracellular signal-regulated kinase 1/2 pathway in regulating osteogenic differentiation of murine preosteoblasts MC3T3-E1 cells on roughened titanium surfaces.Mechanical strain regulates osteoblast proliferation through integrin-mediated ERK activationLentiviral arrays for live-cell dynamic monitoring of gene and pathway activity during stem cell differentiation.GSK-3beta controls osteogenesis through regulating Runx2 activity.Bone Tissue Engineering: Past-Present-Future.Concerted stimuli regulating osteo-chondral differentiation from stem cells: phenotype acquisition regulated by microRNAs.Extracellular matrix remodeling, integrin expression, and downstream signaling pathways influence the osteogenic differentiation of mesenchymal stem cells on poly(lactide-co-glycolide) substrates.BMP-4 induction of arrest and differentiation of osteoblast-like cells via p21 CIP1 and p27 KIP1 regulation.Mitogen-activated protein kinase phosphatase 1/dual specificity phosphatase 1 mediates glucocorticoid inhibition of osteoblast proliferationLysyl oxidase propeptide inhibits FGF-2-induced signaling and proliferation of osteoblasts.Integrin binding specificity regulates biomaterial surface chemistry effects on cell differentiation.The static magnetic field accelerates the osteogenic differentiation and mineralization of dental pulp cells.Thrombospondin-2 facilitates assembly of a type-I collagen-rich matrix in marrow stromal cells undergoing osteoblastic differentiation.Engineering gene expression and protein synthesis by modulation of nuclear shape.Activation of extracellular-signal regulated kinase (ERK1/2) by fluid shear is Ca(2+)- and ATP-dependent in MC3T3-E1 osteoblastsMicroRNA-138 regulates osteogenic differentiation of human stromal (mesenchymal) stem cells in vivo.Differentially expressed genes and signalling pathways are involved in mouse osteoblast-like MC3T3-E1 cells exposed to 17-β estradiol.Sesamin stimulates osteoblast differentiation through p38 and ERK1/2 MAPK signaling pathwaysBMP2-activated Erk/MAP kinase stabilizes Runx2 by increasing p300 levels and histone acetyltransferase activityUse of small interfering ribonucleic acids to inhibit the adipogenic effect of alcohol on human bone marrow-derived mesenchymal cellsP38 and ERK1/2 MAPKs act in opposition to regulate BMP9-induced osteogenic differentiation of mesenchymal progenitor cells.
P2860
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P2860
MAPK pathways activate and phosphorylate the osteoblast-specific transcription factor, Cbfa1.
description
2000 nî lūn-bûn
@nan
2000年の論文
@ja
2000年学术文章
@wuu
2000年学术文章
@zh-cn
2000年学术文章
@zh-hans
2000年学术文章
@zh-my
2000年学术文章
@zh-sg
2000年學術文章
@yue
2000年學術文章
@zh
2000年學術文章
@zh-hant
name
MAPK pathways activate and pho ...... c transcription factor, Cbfa1.
@en
type
label
MAPK pathways activate and pho ...... c transcription factor, Cbfa1.
@en
prefLabel
MAPK pathways activate and pho ...... c transcription factor, Cbfa1.
@en
P2093
P2860
P356
P1476
MAPK pathways activate and pho ...... c transcription factor, Cbfa1.
@en
P2093
G Karsenty
M D Benson
R T Franceschi
P2860
P304
P356
10.1074/JBC.275.6.4453
P407
P577
2000-02-01T00:00:00Z