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Cyclin A and cyclin D1 as significant prognostic markers in colorectal cancer patientsCell cycle regulation of the cyclin A gene promoter is mediated by a variant E2F siteExpression of cyclins and cyclin dependent kinases in human benign and malignant melanocytic lesions.Repression of cyclin D1 expression does not contribute to initiation or maintenance of cell transformation by adenovirus type 5 E1Lead-Induced Cell Cycle Arrest in Human Liver Carcinoma (HepG2) Cells: Involvement of oxidative stress, p53 and Cyclin A.Cyclin D3 predicts disease-free survival in breast cancerA clinicopathological study on overexpression of cyclin D1 and of p53 in a series of 248 patients with operable breast cancerPrognostic significance of CCND1 (cyclin D1) overexpression in primary resected non-small-cell lung cancer.DNA tumor virus oncoproteins and retinoblastoma gene mutations share the ability to relieve the cell's requirement for cyclin D1 function in G1Expression of cyclin D1 correlates with malignancy in human ovarian tumoursCyclin D1 is dispensable for G1 control in retinoblastoma gene-deficient cells independently of cdk4 activity.Prognostic value of CCND1 gene status in sporadic breast tumours, as determined by real-time quantitative PCR assaysKaposi's sarcoma associated herpes virus (KSHV/HHV 8): epidemiology, molecular biology and tissue distribution.Downregulation of cyclin-dependent kinase 2 activity and cyclin A promoter activity in vascular smooth muscle cells by p27(KIP1), an inhibitor of neointima formation in the rat carotid artery.Inhibition of basal and mitogen-stimulated pancreatic cancer cell growth by cyclin D1 antisense is associated with loss of tumorigenicity and potentiation of cytotoxicity to cisplatinum.Cyclin D1 transgene impedes lymphocyte maturation and collaborates in lymphomagenesis with the myc gene.Concerted overexpression of the genes encoding p21 and cyclin D1 is associated with growth inhibition and differentiation in various carcinomas.Induction of cell apoptosis in non-small cell lung cancer cells by cyclin A1 small interfering RNA.Intratumoral delivery of shRNA targeting cyclin D1 attenuates pancreatic cancer growth.Enhanced malignant tumorigenesis in Cdk4 transgenic mice.EBNA-2 and EBNA-LP cooperate to cause G0 to G1 transition during immortalization of resting human B lymphocytes by Epstein-Barr virus.Lack of cyclin D-Cdk complexes in Rb-negative cells correlates with high levels of p16INK4/MTS1 tumour suppressor gene product.Cyclin-dependent kinase-2 (Cdk2) forms an inactive complex with cyclin D1 since Cdk2 associated with cyclin D1 is not phosphorylated by Cdk7-cyclin-H.Oesophageal cancer and amplification of the human cyclin D gene CCND1/PRAD1.Homozygous loss of the MTS1/p16 and MTS2/p15 genes in lymphoma and lymphoblastic leukaemia cell lines.Cyclin D1 and E2F-1 immunoreactivity in bone marrow biopsy specimens of multiple myeloma: relationship to proliferative activity, cytogenetic abnormalities and DNA ploidy.Inhibition of cyclin-dependent kinases by purine analogues.Oncogenic collaboration of the cyclin D1 (PRAD1, bcl-1) gene with a mutated p53 and an activated ras oncogene in neoplastic transformation.Quantitative analysis of cyclin D1 messenger RNA expression in head and neck squamous cell carcinomas.Cyclin D1 overexpression detected by a simple competitive reverse transcription-polymerase chain reaction assay for lymphoid malignancies.
P2860
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P2860
description
1993 nî lūn-bûn
@nan
1993年の論文
@ja
1993年学术文章
@wuu
1993年学术文章
@zh-cn
1993年学术文章
@zh-hans
1993年学术文章
@zh-my
1993年学术文章
@zh-sg
1993年學術文章
@yue
1993年學術文章
@zh
1993年學術文章
@zh-hant
name
Cyclins and oncogenesis.
@en
type
label
Cyclins and oncogenesis.
@en
prefLabel
Cyclins and oncogenesis.
@en
P1476
Cyclins and oncogenesis.
@en
P2093
P356
10.1016/0304-419X(93)90022-5
P577
1993-05-01T00:00:00Z