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CCN6: a novel method of aTAKing cancer

CCN6: a novel method of aTAKing cancer

http://www.wikidata.org/entity/Q40914018

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Eyeing the Cyr61/CTGF/NOV (CCN) group of genes in development and diseases: highlights of their structural likenesses and functional dissimilarities WISP3 is highly expressed in a subset of colorectal carcinomas with a better prognosis.

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P2860

CCN6: a novel method of aTAKing cancer

http://www.wikidata.org/entity/Q40914018

description

2013 nî lūn-bûn

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2013年の論文

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2013年学术文章

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2013年学术文章

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2013年学术文章

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2013年学术文章

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2013年学术文章

@zh-sg

2013年學術文章

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2013年學術文章

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2013年學術文章

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name

CCN6: a novel method of aTAKing cancer

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CCN6: a novel method of aTAKing cancer

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CCN6: a novel method of aTAKing cancer

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S12079-012-0189-8

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Journal of Cell Communication and Signaling

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CCN6: a novel method of aTAKing cancer

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Andrew Leask

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P2860

The CCN family of proteins: structure-function relationships

Taking aim at the extracellular matrix: CCN proteins as emerging therapeutic targets

All in the CCN family: essential matricellular signaling modulators emerge from the bunker

NOV (nephroblastoma overexpressed) and the CCN family of genes: structural and functional issues.

CCN6 modulates BMP signaling via the Smad-independent TAK1/p38 pathway, acting to suppress metastasis of breast cancer.

Inhibition of CCN6 (Wnt-1-induced signaling protein 3) down-regulates E-cadherin in the breast epithelium through induction of snail and ZEB1.

Targeting of TAK1 in inflammatory disorders and cancer.

Blockade of CCN6 (WISP3) activates growth factor-independent survival and resistance to anoikis in human mammary epithelial cells.

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s12079-012-0189-8

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161-162

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scholarly article

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10.1007/S12079-012-0189-8

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2

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23292930

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3660687

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