The neurotoxin MPTP causes degeneration of specific nucleus A8, A9 and A10 dopaminergic neurons in the mouse.
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Double-knockout mice for alpha- and beta-synucleins: effect on synaptic functionsGenetic variability of respiratory complex abundance, organization and activity in mouse brainDifferential effects of intrastriatal 6-hydroxydopamine on cell number and morphology in midbrain dopaminergic subregions of the ratThe neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine induces apoptosis in mouse nigrostriatal glia. Relevance to nigral neuronal death and striatal neurochemical changes.In vivo measures of nigrostriatal neuronal response to unilateral MPTP treatment.MPTP treatment increases expression of pre-pro-nociceptin/orphanin FQ mRNA in a subset of substantia nigra reticulata neurons.Using 'omics' to define pathogenesis and biomarkers of Parkinson's disease.Neuromelanin in the human brain: a review and atlas of pigmented cells in the substantia nigra.Quantitative assessment of gait and neurochemical correlation in a classical murine model of Parkinson's disease.Defining midbrain dopaminergic neuron diversity by single-cell gene expression profiling.Proteomic identification of proteins in the human brain: Towards a more comprehensive understanding of neurodegenerative diseaseTemporal mRNA profiles of inflammatory mediators in the murine 1-methyl-4-phenyl-1,2,3,6-tetrahydropyrimidine model of Parkinson's diseaseHIF1α is necessary for exercise-induced neuroprotection while HIF2α is needed for dopaminergic neuron survival in the substantia nigra pars compacta.Long-lasting transcriptional refractoriness triggered by a single exposure to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyrimidineAgeing as a primary risk factor for Parkinson's disease: evidence from studies of non-human primates.Poly(ADP-ribose) polymerase activation mediates 1-methyl-4-phenyl-1, 2,3,6-tetrahydropyridine (MPTP)-induced parkinsonism.Infiltration of CD4+ lymphocytes into the brain contributes to neurodegeneration in a mouse model of Parkinson disease.Distinct mechanisms of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyrimidine resistance revealed by transcriptome mapping in mouse striatum.Excess "read-through" acetylcholinesterase attenuates but the "synaptic" variant intensifies neurodeterioration correlates.The angiotensin converting enzyme inhibitor captopril protects nigrostriatal dopamine neurons in animal models of parkinsonismAnalysis of monocyte infiltration in MPTP mice reveals that microglial CX3CR1 protects against neurotoxic over-induction of monocyte-attracting CCL2 by astrocytes.MPTP mouse models of Parkinson's disease: an update.Molecular determinants of selective dopaminergic vulnerability in Parkinson's disease: an update.Alternative microglial activation is associated with cessation of progressive dopamine neuron loss in mice systemically administered lipopolysaccharide.Single low doses of MPTP decrease tyrosine hydroxylase expression in the absence of overt neuron loss.Dopamine and α-synuclein dysfunction in Smad3 null miceTranscriptome Profile Changes in Mice with MPTP-Induced Early Stages of Parkinson's Disease.MPP(+) -dependent inhibition of Ih reduces spontaneous activity and enhances EPSP summation in nigral dopamine neuronsCalbindin content and differential vulnerability of midbrain efferent dopaminergic neurons in macaques.Antioxidant Formulae, Shengmai San, and LingGuiZhuGanTang, Prevent MPTP Induced Brain Dysfunction and Oxidative Damage in MiceA viral peptide that targets mitochondria protects against neuronal degeneration in models of Parkinson's disease.Association of social defeat stress-induced anhedonia-like symptoms with mGluR1-dependent decrease in membrane-bound AMPA-GluR1 in the mouse ventral midbrain.Dopamine transporter-immunoreactive neurons decrease with age in the human substantia nigra.Manganese does not alter the severe neurotoxicity of MPTP.Attenuation of MPTP-induced neurotoxicity and locomotor dysfunction in Nucling-deficient mice via suppression of the apoptosome pathway.Analysis of VMAT2 binding after methamphetamine or MPTP treatment: disparity between homogenates and vesicle preparations.
P2860
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P2860
The neurotoxin MPTP causes degeneration of specific nucleus A8, A9 and A10 dopaminergic neurons in the mouse.
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年学术文章
@wuu
1996年学术文章
@zh-cn
1996年学术文章
@zh-hans
1996年学术文章
@zh-my
1996年学术文章
@zh-sg
1996年學術文章
@yue
1996年學術文章
@zh
1996年學術文章
@zh-hant
name
The neurotoxin MPTP causes deg ...... minergic neurons in the mouse.
@en
type
label
The neurotoxin MPTP causes deg ...... minergic neurons in the mouse.
@en
prefLabel
The neurotoxin MPTP causes deg ...... minergic neurons in the mouse.
@en
P2093
P356
P1476
The neurotoxin MPTP causes deg ...... minergic neurons in the mouse.
@en
P2093
P304
P356
10.1006/NEUR.1996.0041
P407
P577
1996-12-01T00:00:00Z