A bipartite nuclear localization signal is required for p53 nuclear import regulated by a carboxyl-terminal domain.
about
Cloning and characterization of a p53-related protein kinase expressed in interleukin-2-activated cytotoxic T-cells, epithelial tumor cell lines, and the testesThe RNA binding protein nuclear factor 90 functions as both a positive and negative regulator of gene expression in mammalian cellsInduction of apoptosis by cytoplasmically localized wild-type p53 and the S121F mutant super p53Regulation of p53 tetramerization and nuclear export by ARCImportin-alpha mediates the regulated nuclear targeting of serum- and glucocorticoid-inducible protein kinase (Sgk) by recognition of a nuclear localization signal in the kinase central domainG2E3 is a nucleo-cytoplasmic shuttling protein with DNA damage responsive localizationInvolvement of p53 in the repair of DNA double strand breaks: multifaceted Roles of p53 in homologous recombination repair (HRR) and non-homologous end joining (NHEJ)G-actin guides p53 nuclear transport: potential contribution of monomeric actin in altered localization of mutant p53.Prenylation-dependent association of protein-tyrosine phosphatases PRL-1, -2, and -3 with the plasma membrane and the early endosomeA role for Hsc70 in regulating nucleocytoplasmic transport of a temperature-sensitive p53 (p53Val-135)Nuclear localization of Tob is important for regulation of its antiproliferative activityA better experimental method to detect the sensitivity of cancer cells to anticancer drugs after adenovirus-mediated introduction of two kinds of p53 in vivoThe transcription factor SOX9 regulates cell cycle and differentiation genes in chondrocytic CFK2 cellsP53 is transported into the nucleus via an Hsf1-dependent nuclear localization mechanismThe p53-induced factor Ei24 inhibits nuclear import through an importin β-binding-like domainCell cycle-dependent and DNA damage-inducible nuclear localization of FEN-1 nuclease is consistent with its dual functions in DNA replication and repair.Discovery of novel proteasome inhibitors using a high-content cell-based screening systemImpaired p53 binding to importin: a novel mechanism of cytoplasmic sequestration identified in oxaliplatin-resistant cells.Conservation of complex nuclear localization signals utilizing classical and non-classical nuclear import pathways in LANA homologs of KSHV and RFHVDial 9-1-1 for p53: mechanisms of p53 activation by cellular stressProtein mislocalization: mechanisms, functions and clinical applications in cancer.Baculovirus transregulator IE1 requires a dimeric nuclear localization element for nuclear import and promoter activation.Control of protein function through optochemical translocationMice defective in p53 nuclear localization signal 1 exhibit exencephaly.Defects in virion production caused by mutations affecting the C-terminal portion of the Moloney murine leukemia virus capsid protein.Importin alpha-mediated nuclear import of cytoplasmic poly(A) binding protein occurs as a direct consequence of cytoplasmic mRNA depletionStress-mediated nuclear stabilization of p53 is regulated by ubiquitination and importin-alpha3 bindingSpecific amino acid residues in the basic helix-loop-helix domain of SRC-3 are essential for its nuclear localization and proteasome-dependent turnover.Critical role of N-terminal end-localized nuclear export signal in regulation of activating transcription factor 2 (ATF2) subcellular localization and transcriptional activity.Nucleocytoplasmic shuttling of p53 is essential for MDM2-mediated cytoplasmic degradation but not ubiquitinationLeucine-Rich Repeat Kinase 2 (LRRK2) phosphorylates p53 and induces p21(WAF1/CIP1) expressionProtein kinase Cα (PKCα) regulates p53 localization and melanoma cell survival downstream of integrin αv in three-dimensional collagen and in vivoGenetic analysis of p53 nuclear importationHsf1 is required for the nuclear translocation of p53 tumor suppressorExploring genomic alteration in pediatric cancer using ProteinPaintFunctional characterization of p53 pathway components in the ancient metazoan Trichoplax adhaerensIdentification of CASZ1 NES reveals potential mechanisms for loss of CASZ1 tumor suppressor activity in neuroblastoma.Krüppel-like zinc fingers bind to nuclear import proteins and are required for efficient nuclear localization of erythroid Krüppel-like factor.Nuclear import and export signals in control of the p53-related protein p73.A truncated p53 in human lung cancer cells as a critical determinant of proliferation and invasiveness.
P2860
Q24291659-022057E9-DC6A-46EF-952A-BBD6DEF8824BQ24291990-163ECA15-0EA8-4ADC-80F1-9B746CE42EC6Q24293008-63E5409F-AFB8-44EC-9205-66D86E380F91Q24304068-A4122693-8CA9-4051-85A6-6D93A3EB7D6EQ24554299-7C40FA04-8433-4CA5-9FCA-70C2C6FF4C78Q24681594-20C516C1-BED4-4040-AAB4-5026C7287523Q27002581-5127D9D6-60C6-4F2F-8A1E-F993E9F4BBC7Q27313430-293371C9-4FF2-4878-9DF0-AE5D98030DD4Q28140543-F7179830-B733-48E7-BBBD-49815966F73CQ28211719-5D332CAB-F4BA-4614-8481-9E43632033D8Q28270343-C545233A-9C27-4FDF-A408-4F9E28F772E3Q28546961-FCB63AD5-275E-4E48-9BC0-BC8948398D09Q28570025-175E9304-CDEB-4C46-97DB-61208F13FBFCQ28581134-5EB0A379-3B20-4373-A02D-180B7309B445Q28592298-56D5E8DC-26A3-4970-A789-2D8D2B78279CQ31505231-0438C1A0-4430-486E-8B43-057F632850BDQ33521189-20C7BCB5-A978-4B14-B8BC-AA12F8D815B4Q33840099-3574D779-1D7D-4662-A491-0ABDC3F956ADQ33895240-FEEFF3B4-F631-4EE7-A651-8BA3A6F5653FQ33997846-96E91444-A758-435E-9729-14033A80540BQ34076405-5DB0EAE5-FF1C-499F-BB20-03FD0A2E6729Q34346146-B9C4B29A-025C-41F2-9244-474D52FE63FBQ34408224-CE47E202-509B-4C6A-9241-7EDC53BBEE1AQ34523129-8BFC7BDC-6388-407C-9DEB-3920F161D576Q34755046-1888B3AF-E903-4AEF-8265-B5F2528E20BAQ35139425-FFFB3749-E085-4E75-A0C4-E5E6B0E27B5BQ35569661-1B1A83A0-54E3-4E4A-86E1-37F3298BBF37Q35641931-1D2899BD-16BD-486F-B8E1-40C1B00141CAQ35868135-D345E41A-7AEB-41BF-A3AC-C6FCA9463A0BQ35920894-EC4F37B0-3DE0-463A-B105-A7ADC2BFB818Q36073860-231D9FF9-A28C-44DA-B822-1922A42121D9Q36215857-BB5E95E2-0F56-4E9A-85D1-B2DB0731AF62Q36398846-2887E2C4-C724-44F2-B779-3AC60DD859AEQ36897770-683FA8DD-85AE-48F8-98B6-BBA7806C3C00Q36967018-1E3F1F83-ED23-4070-952D-7FE50C82816EQ37291405-22749E4A-89F7-4E0A-A3CA-BAFB05110F91Q37478609-F18A3DC9-5AB7-4A30-B922-C4F587CBB3C7Q38287997-12ED4D75-3BA1-42FA-88F0-C692B3D8F6A6Q38292032-BC4A7C04-8FC9-4FC0-BBE8-E894453969D9Q38699698-0B9D2A3D-EFBC-4C5B-9505-D659F98FCB3A
P2860
A bipartite nuclear localization signal is required for p53 nuclear import regulated by a carboxyl-terminal domain.
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年学术文章
@wuu
1999年学术文章
@zh-cn
1999年学术文章
@zh-hans
1999年学术文章
@zh-my
1999年学术文章
@zh-sg
1999年學術文章
@yue
1999年學術文章
@zh
1999年學術文章
@zh-hant
name
A bipartite nuclear localizati ...... by a carboxyl-terminal domain.
@en
type
label
A bipartite nuclear localizati ...... by a carboxyl-terminal domain.
@en
prefLabel
A bipartite nuclear localizati ...... by a carboxyl-terminal domain.
@en
P356
P1476
A bipartite nuclear localizati ...... by a carboxyl-terminal domain.
@en
P2093
P304
32699-32703
P356
10.1074/JBC.274.46.32699
P407
P577
1999-11-01T00:00:00Z