Tyrosine phosphorylation of C-Cbl facilitates adhesion and spreading while suppressing anchorage-independent growth of V-Abl-transformed NIH3T3 fibroblasts.
about
Membrane-anchored Cbl suppresses Hck protein-tyrosine kinase mediated cellular transformationc-Cbl facilitates fibronectin matrix production by v-Abl-transformed NIH3T3 cells via activation of small GTPasesRapid ubiquitination of Syk following GPVI activation in plateletsCatalytic domains of tyrosine kinases determine the phosphorylation sites within c-Cbl.Interaction of c-Cbl with myosin IIA regulates Bleb associated macropinocytosis of Kaposi's sarcoma-associated herpesvirus.Loss of Cbl-PI3K interaction in mice prevents significant bone loss following ovariectomyCbl: many adaptations to regulate protein tyrosine kinases.The loss of Cbl-phosphatidylinositol 3-kinase interaction perturbs RANKL-mediated signaling, inhibiting bone resorption and promoting osteoclast survival.Beyond the RING: CBL proteins as multivalent adapters.Cbl-transforming variants trigger a cascade of molecular alterations that lead to epithelial mesenchymal conversionAbrogation of Cbl-PI3K interaction increases bone formation and osteoblast proliferation.Role of Cbl-PI3K Interaction during Skeletal Remodeling in a Murine Model of Bone Repair.Cbl-3-deficient mice exhibit normal epithelial developmentLoss of Cbl-PI3K interaction modulates the periosteal response to fracture by enhancing osteogenic commitment and differentiation.Loss of Cbl-PI3K interaction enhances osteoclast survival due to p21-Ras mediated PI3K activation independent of Cbl-bAn essential role of ubiquitination in Cbl-mediated negative regulation of the Src-family kinase Fyn.Cbl proteins in platelet activation.Cbl-family proteins as regulators of cytoskeleton-dependent phenomena.IGF-I receptor signaling in a prostatic cancer cell line with a PTEN mutation.The proto-oncogene c-Cbl is a positive regulator of Met-induced MAP kinase activation: a role for the adaptor protein Crk.CD93 and dystroglycan cooperation in human endothelial cell adhesion and migration adhesion and migration.c-Cbl-facilitated cytoskeletal effects in v-Abl-transformed fibroblasts are regulated by membrane association of c-Cbl.Activation of Rho is required for ligand-independent oncogenic signaling by a mutant epidermal growth factor receptor.c-Cbl regulates glioma invasion through matrix metalloproteinase 2.
P2860
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P2860
Tyrosine phosphorylation of C-Cbl facilitates adhesion and spreading while suppressing anchorage-independent growth of V-Abl-transformed NIH3T3 fibroblasts.
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
1999年论文
@zh
1999年论文
@zh-cn
name
Tyrosine phosphorylation of C- ...... ransformed NIH3T3 fibroblasts.
@en
type
label
Tyrosine phosphorylation of C- ...... ransformed NIH3T3 fibroblasts.
@en
prefLabel
Tyrosine phosphorylation of C- ...... ransformed NIH3T3 fibroblasts.
@en
P2093
P2860
P356
P1433
P1476
Tyrosine phosphorylation of C- ...... ransformed NIH3T3 fibroblasts.
@en
P2093
A Y Tsygankov
E A Feshchenko
P2860
P2888
P304
P356
10.1038/SJ.ONC.1202672
P407
P577
1999-06-01T00:00:00Z
P5875
P6179
1007787178