A role for methylation of the hMLH1 promoter in loss of hMLH1 expression and drug resistance in ovarian cancer.
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Human exonuclease I is required for 5' and 3' mismatch repairMutS homologue hMSH5: role in cisplatin-induced DNA damage responseEpigenetics as a mechanism driving polygenic clinical drug resistanceGenomic/Epigenomic Alterations in Ovarian Carcinoma: Translational Insight into Clinical PracticeThe clinical value of aberrant epigenetic changes of DNA damage repair genes in human cancerDNA methylation changes in epithelial ovarian cancer histotypes.Predictive value of CHFR and MLH1 methylation in human gastric cancer.Chemoresistance and targeted therapies in ovarian and endometrial cancersEpigenome-based personalized medicine in human cancerIncreased microsatellite instability and epigenetic inactivation of the hMLH1 gene in head and neck squamous cell carcinomaA review of the clinical relevance of mismatch-repair deficiency in ovarian cancerDocetaxel-carboplatin as first line chemotherapy for epithelial ovarian cancerReduced expression of intercellular adhesion molecule-1 in ovarian adenocarcinomasSensitization by 5-aza-2'-deoxycytidine of leukaemia cells with MLL abnormalities to induction of differentiation by all-trans retinoic acid and 1alpha,25-dihydroxyvitamin D3.Mismatch repair and treatment resistance in ovarian cancer.Dihydroimidazophenanthridinium (DIP)-based DNA binding agents with tuneable structures and biological activity.Integrated analysis of DNA methylation and gene expression reveals specific signaling pathways associated with platinum resistance in ovarian cancerFunctions of MutLalpha, replication protein A (RPA), and HMGB1 in 5'-directed mismatch repairDNA methylation profiles of ovarian epithelial carcinoma tumors and cell lines.Epigenetic therapies for chemoresensitization of epithelial ovarian cancer.DNA methylation and Transcriptome Changes Associated with Cisplatin Resistance in Ovarian Cancer.DNA polymerases as potential therapeutic targets for cancers deficient in the DNA mismatch repair proteins MSH2 or MLH1DNA methylation profiles in ovarian cancer: implication in diagnosis and therapy (Review)Alterations in p53 predict response to preoperative high dose chemotherapy in patients with gastric cancerMessenger RNA expression and methylation of candidate tumor-suppressor genes and risk of ovarian cancer-a case-control analysisNitric oxide: perspectives and emerging studies of a well known cytotoxinDNA methylation: an alternative pathway to cancer.FT-IR microspectrometry reveals the variation of membrane polarizability due to epigenomic effect on epithelial ovarian cancerMismatch repair status and outcomes after adjuvant therapy in patients with surgically staged endometrial cancer.Phase 1b-2a study to reverse platinum resistance through use of a hypomethylating agent, azacitidine, in patients with platinum-resistant or platinum-refractory epithelial ovarian cancerGenome-wide epigenetic modifications in cancer.Reactivating the expression of methylation silenced genes in human cancer.Methylation and protein expression of DNA repair genes: association with chemotherapy exposure and survival in sporadic ovarian and peritoneal carcinomasFrequency of mismatch repair deficiency in ovarian cancer: a systematic review This article is a US Government work and, as such, is in the public domain of the United States of America.Selecting bioactive phenolic compounds as potential agents to inhibit proliferation and VEGF expression in human ovarian cancer cells.Candidate tumor-suppressor gene DLEC1 is frequently downregulated by promoter hypermethylation and histone hypoacetylation in human epithelial ovarian cancer.YY1 suppresses FEN1 over-expression and drug resistance in breast cancerMethylated DNA as a possible screening marker for neoplastic disease in several body fluids.Identification and evaluation of a potent novel ATR inhibitor, NU6027, in breast and ovarian cancer cell linesCancer epigenetics: linking basic biology to clinical medicine.
P2860
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P2860
A role for methylation of the hMLH1 promoter in loss of hMLH1 expression and drug resistance in ovarian cancer.
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
1999年论文
@zh
1999年论文
@zh-cn
name
A role for methylation of the ...... resistance in ovarian cancer.
@en
type
label
A role for methylation of the ...... resistance in ovarian cancer.
@en
prefLabel
A role for methylation of the ...... resistance in ovarian cancer.
@en
P2093
P2860
P356
P1433
P1476
A role for methylation of the ...... resistance in ovarian cancer.
@en
P2093
P2860
P2888
P304
P356
10.1038/SJ.ONC.1202540
P407
P577
1999-04-01T00:00:00Z
P5875
P6179
1028453288