In hybridoma cultures, deprivation of any single amino acid leads to apoptotic death, which is suppressed by the expression of the bcl-2 gene.
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Assay of the multiple energy-producing pathways of mammalian cellsConstraints on the transport and glycosylation of recombinant IFN-gamma in Chinese hamster ovary and insect cells.cMyc increases cell number through uncoupling of cell division from cell size in CHO cells.Amino acids regulate transgene expression in MDCK cells.Determination of amino acids and catecholamines derivatized with 3-(4-chlorobenzoyl)-2-quinolinecarboxaldehyde in PC12 and HEK293 cells by capillary electrophoresis with laser-induced fluorescence detection.Production of recombinant protein therapeutics in cultivated mammalian cells.Bacterial lysine decarboxylase influences human dental biofilm lysine content, biofilm accumulation, and subclinical gingival inflammationTranslational regulation in cell stress and apoptosis. Roles of the eIF4E binding proteins.Patterns of amino acid metabolism by proliferating human mesenchymal stem cells.Advances in monoclonal antibody technology: genetic engineering of mice, cells, and immunoglobulins.Techniques for dual staining of DNA and intracellular immunoglobulins in murine hybridoma cells: applications to cell-cycle analysis of hyperosmotic cultures.Variable functions of bcl-2 in mediating bioreactor stress- induced apoptosis in hybridoma cellsUsing cell engineering and omic tools for the improvement of cell culture processes.Engineering mammalian cells in bioprocessing - current achievements and future perspectives.Cell death in mammalian cell culture: molecular mechanisms and cell line engineering strategiesExpression of the transcription factor GADD153 is an indicator of apoptosis for recombinant chinese hamster ovary (CHO) cells.Population-based modeling of the progression of apoptosis in mammalian cell culture.Autophagy and apoptosis of recombinant Chinese hamster ovary cells during fed-batch culture: effect of nutrient supplementation.Chemostat-based transcriptional analysis of growth rate change and BCL-2 over-expression in NS0 cells.Prolongation of murine hybridoma cell survival in stationary batch culture by Bcl-xL expression.Apoptosis and its suppression in hepatocytes culture.Regulated overexpression of the survival factor bcl-2 in CHO cells increases viable cell density in batch culture and decreases DNA release in extended fixed-bed cultivation.Fed-batch culture optimization of a growth-associated hybridoma cell line in chemically defined protein-free media.Enhanced cell culture performance using inducible anti-apoptotic genes E1B-19K and Aven in the production of a monoclonal antibody with Chinese hamster ovary cells.Comparison of Bcl-2 to a Bcl-2 deletion mutant for mammalian cells exposed to culture insults.Influence of bcl-2 on cell death during the cultivation of a Chinese hamster ovary cell line expressing a chimeric antibody.Bcl-2 over-expression reduces growth rate and prolongs G1 phase in continuous chemostat cultures of hybridoma cells.The role of vitamins and amino acids on hybridoma growth and monoclonal antibody production.On-line heat flux measurements improve the culture medium for the growth and productivity of genetically engineered CHO cells.Protection of hybridoma cells against apoptosis by a loop domain-deficient Bcl-xL protein.Simultaneous measurement of 19 components in serum-containing animal cell culture media by fourier transform near-infrared spectroscopy.Pharmacokinetic, pharmacodynamic and intracellular effects of PEG-asparaginase in newly diagnosed childhood acute lymphoblastic leukemia: results from a single agent window study.Impact of coexpression and coamplification of sICAM and antiapoptosis determinants bcl-2/bcl-x(L) on productivity, cell survival, and mitochondria number in CHO-DG44 grown in suspension and serum-free media.A mathematical model of caspase function in apoptosis.Mitochondrial membrane potential differentiates cells resistant to apoptosis in hybridoma cultures.Part II. Overexpression of bcl-2 family members enhances survival of mammalian cells in response to various culture insults.Apoptosis-resistant E1B-19K-expressing NS/0 myeloma cells exhibit increased viability and chimeric antibody productivity under perfusion culture conditions.
P2860
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P2860
In hybridoma cultures, deprivation of any single amino acid leads to apoptotic death, which is suppressed by the expression of the bcl-2 gene.
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
1998年论文
@zh
1998年论文
@zh-cn
name
In hybridoma cultures, depriva ...... expression of the bcl-2 gene.
@en
type
label
In hybridoma cultures, depriva ...... expression of the bcl-2 gene.
@en
prefLabel
In hybridoma cultures, depriva ...... expression of the bcl-2 gene.
@en
P2093
P2860
P1476
In hybridoma cultures, depriva ...... expression of the bcl-2 gene.
@en
P2093
P2860
P356
10.1002/(SICI)1097-0290(19980705)59:1<90::AID-BIT12>3.0.CO;2-6
P577
1998-07-01T00:00:00Z