On the mechanism of rifampicin inhibition of RNA synthesis.
about
GE23077 binds to the RNA polymerase 'i' and 'i+1' sites and prevents the binding of initiating nucleotidesStructures of RNA polymerase-antibiotic complexesDirect detection of abortive RNA transcripts in vivoRifamycins do not function by allosteric modulation of binding of Mg2+ to the RNA polymerase active centerX-ray Crystal Structures of the Escherichia coli RNA Polymerase in Complex with BenzoxazinorifamycinsTranscription inhibition by the depsipeptide antibiotic salinamide AEfflux pump gene expression in multidrug-resistant Mycobacterium tuberculosis clinical isolatesTranslocation after synthesis of a four-nucleotide RNA commits RNA polymerase II to promoter escapeMolecular evolution of multisubunit RNA polymerases: structural analysisDNA bending and wrapping around RNA polymerase: a "revolutionary" model describing transcriptional mechanisms.Escherichia coli transcript cleavage factors GreA and GreB stimulate promoter escape and gene expression in vivo and in vitroDifferent rifampin sensitivities of Escherichia coli and Mycobacterium tuberculosis RNA polymerases are not explained by the difference in the beta-subunit rifampin regions I and II.Cross-resistance of Escherichia coli RNA polymerases conferring rifampin resistance to different antibiotics.Rifaximin modulates the vaginal microbiome and metabolome in women affected by bacterial vaginosis.Structural, functional, and genetic analysis of sorangicin inhibition of bacterial RNA polymerase.Immobilization of Escherichia coli RNA polymerase and location of binding sites by use of chromatin immunoprecipitation and microarrays.How antibiotics kill bacteria: from targets to networksOverproduction of three genes leads to camphor resistance and chromosome condensation in Escherichia coli.Distance-restrained docking of rifampicin and rifamycin SV to RNA polymerase using systematic FRET measurements: developing benchmarks of model quality and reliability.Studies of the distribution of Escherichia coli cAMP-receptor protein and RNA polymerase along the E. coli chromosome.Physical interference between escherichia coli RNA polymerase molecules transcribing in tandem enhances abortive synthesis and misincorporation.Protein inactivation in mycobacteria by controlled proteolysis and its application to deplete the beta subunit of RNA polymerase.RNA polymerase: linear competitive inhibition by bis-(3' to 5')-cyclic dinucleotides,NpNpTargeting Mycobacterium tuberculosis topoisomerase I by small-molecule inhibitors.Unfolding of the bacterial nucleoid both in vivo and in vitro as a result of exposure to camphor.Optimization and Evaluation of 5-Styryl-Oxathiazol-2-one Mycobacterium tuberculosis Proteasome Inhibitors as Potential Antitubercular Agents.Mutation analysis of mycobacterial rpoB genes and rifampin resistance using recombinant Mycobacterium smegmatis.Topology of the RNA polymerase active center probed by chimeric rifampicin-nucleotide compounds.Effect of salts on abortive and productive elongation catalysed by wheat germ RNA polymerase IIProduction and characterization of a highly pure RNA polymerase holoenzyme from Mycobacterium tuberculosis.Affinity Selection-Mass Spectrometry Identifies a Novel Antibacterial RNA Polymerase Inhibitor.Structural perspective on mutations affecting the function of multisubunit RNA polymerases.Study of the rifampin monoresistance mechanism in Mycobacterium tuberculosis.In vitro analysis of elongation and termination by mutant RNA polymerases with altered termination behaviorBacterial Transcription as a Target for Antibacterial Drug Development.Effects of silver nanoparticles in combination with antibiotics on the resistant bacteria Acinetobacter baumannii.RNA Polymerase Pausing during Initial Transcription.Epistasis between antibiotic resistance mutations drives the evolution of extensively drug-resistant tuberculosis.RNA polymerase active center: the molecular engine of transcription.Depleting Mycobacterium tuberculosis of the transcription termination factor Rho causes pervasive transcription and rapid death
P2860
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P2860
On the mechanism of rifampicin inhibition of RNA synthesis.
description
1978 nî lūn-bûn
@nan
1978年の論文
@ja
1978年論文
@yue
1978年論文
@zh-hant
1978年論文
@zh-hk
1978年論文
@zh-mo
1978年論文
@zh-tw
1978年论文
@wuu
1978年论文
@zh
1978年论文
@zh-cn
name
On the mechanism of rifampicin inhibition of RNA synthesis.
@en
type
label
On the mechanism of rifampicin inhibition of RNA synthesis.
@en
prefLabel
On the mechanism of rifampicin inhibition of RNA synthesis.
@en
P1476
On the mechanism of rifampicin inhibition of RNA synthesis.
@en
P2093
P304
P407
P577
1978-12-01T00:00:00Z