Antitumor effect of allogenic fibroblasts engineered to express Fas ligand (FasL).
about
Natural selection of tumor variants in the generation of "tumor escape" phenotypesFas receptor-mediated apoptosis: a clinical application?Polymorphonuclear neutrophils and cancer: intense and sustained neutrophilia as a treatment against solid tumors.Tumor evasion from T cell surveillance.Cell death-independent activities of the death receptors CD95, TRAILR1, and TRAILR2.Efficient nonviral gene therapy with FasL and Del1 fragments in mice.Pre-existing Fas ligand (FasL) in cancer cells elicits tumor-specific protective immunity, but delayed induction of FasL expression after inoculation facilitates tumor formation.Nonviral genetic transfer of Fas ligand induced significant growth suppression and apoptotic tumor cell death in prostate cancer in vivo.The effects of FasL on inflammation and tumor survival are dependent on its expression levels.Fas ligand-expressing tumors induce tumor-specific protective immunity in the inoculated hosts but vaccination with the apoptotic tumors suppresses antitumor immunity.
P2860
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P2860
Antitumor effect of allogenic fibroblasts engineered to express Fas ligand (FasL).
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
1998年论文
@zh
1998年论文
@zh-cn
name
Antitumor effect of allogenic fibroblasts engineered to express Fas ligand (FasL).
@en
type
label
Antitumor effect of allogenic fibroblasts engineered to express Fas ligand (FasL).
@en
prefLabel
Antitumor effect of allogenic fibroblasts engineered to express Fas ligand (FasL).
@en
P2093
P356
P1433
P1476
Antitumor effect of allogenic fibroblasts engineered to express Fas ligand (FasL).
@en
P2093
P2888
P304
P356
10.1038/SJ.GT.3300763
P577
1998-12-01T00:00:00Z
P5875
P6179
1051271155