Identification of microglial signal transduction pathways mediating a neurotoxic response to amyloidogenic fragments of beta-amyloid and prion proteins.
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Down-regulation of DENN/MADD, a TNF receptor binding protein, correlates with neuronal cell death in Alzheimer's disease brain and hippocampal neuronsBiomarkers of Alzheimer's diseaseReduction of human monocytic cell neurotoxicity and cytokine secretion by ligands of the cannabinoid-type CB2 receptorDifferential regulation of Abeta42-induced neuronal C1q synthesis and microglial activationStress Granules Modulate SYK to Cause Microglial Cell Dysfunction in Alzheimer's Disease.Functional impairment of microglia coincides with Beta-amyloid deposition in mice with Alzheimer-like pathologyDo Microglia Default on Network Maintenance in Alzheimer's Disease?Inflammation and Alzheimer's diseaseCharacterization of Novel Src Family Kinase Inhibitors to Attenuate MicrogliosisCD45RB is a novel molecular therapeutic target to inhibit Abeta peptide-induced microglial MAPK activation.Genomic convergence and network analysis approach to identify candidate genes in Alzheimer's disease.Molecular mechanisms of neurodegeneration in Alzheimer's disease.Tracking neuroinflammation in Alzheimer's disease: the role of positron emission tomography imaging.Microglial activation and neuroinflammation in Alzheimer's disease: a critical examination of recent history.Central administration of interleukin-4 exacerbates hypothalamic inflammation and weight gain during high-fat feedingAmyloid precursor protein expression modulates intestine immune phenotype.A novel cell line from spontaneously immortalized murine microglia.Amyloid precursor protein and proinflammatory changes are regulated in brain and adipose tissue in a murine model of high fat diet-induced obesity.CD36 participates in PrP(106-126)-induced activation of microglia.Ibuprofen attenuates oxidative damage through NOX2 inhibition in Alzheimer's diseaseThe spleen tyrosine kinase (Syk) regulates Alzheimer amyloid-β production and Tau hyperphosphorylation.Adaptors for disorders of the brain? The cancer signaling proteins NEDD9, CASS4, and PTK2B in Alzheimer's disease.Macrophage Migration Inhibitory Factor is subjected to glucose modification and oxidation in Alzheimer's Disease.Development of kinomic analyses to identify dysregulated signaling pathways in cells expressing cytoplasmic PrP.IFN-gamma receptor signaling mediates spinal microglia activation driving neuropathic painThe microglial NADPH oxidase complex as a source of oxidative stress in Alzheimer's diseaseAttenuation of microglial activation in a mouse model of Alzheimer's disease via NFAT inhibitionMicroglia Activate Migration of Glioma Cells through a Pyk2 Intracellular Pathway.The toxicity of the PrP106-126 prion peptide on cultured photoreceptors correlates with the prion protein distribution in the mammalian and human retina.NADPH oxidase and reactive oxygen species contribute to alcohol-induced microglial activation and neurodegeneration.Amyloid-β oligomers stimulate microglia through a tyrosine kinase dependent mechanism.Inhibition of Src kinase activity attenuates amyloid associated microgliosis in a murine model of Alzheimer's disease.The endocytic pathway in microglia during health, aging and Alzheimer's disease.Early induction of interferon-responsive mRNAs in Creutzfeldt-Jakob diseaseYoung microglia restore amyloid plaque clearance of aged microglia.Microglia play a role in ethanol-induced oxidative stress and apoptosis in developing hypothalamic neurons.Loss of interleukin receptor-associated kinase 4 signaling suppresses amyloid pathology and alters microglial phenotype in a mouse model of Alzheimer's disease.1-42 β-amyloid peptide requires PDK1/nPKC/Rac 1 pathway to induce neuronal death.Role of CD40 in prion disease and the immune response to recombinant PrPBeta amyloid oligomers and fibrils stimulate differential activation of primary microglia
P2860
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P2860
Identification of microglial signal transduction pathways mediating a neurotoxic response to amyloidogenic fragments of beta-amyloid and prion proteins.
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
1999年论文
@zh
1999年论文
@zh-cn
name
Identification of microglial s ...... ta-amyloid and prion proteins.
@en
type
label
Identification of microglial s ...... ta-amyloid and prion proteins.
@en
prefLabel
Identification of microglial s ...... ta-amyloid and prion proteins.
@en
P2093
P921
P1476
Identification of microglial s ...... ta-amyloid and prion proteins.
@en
P2093
D E Johnson
G E Landreth
S B Cannady
T M Lehman
P304
P407
P577
1999-02-01T00:00:00Z