Dbf4 and Cdc7 proteins promote DNA replication through interactions with distinct Mcm2-7 protein subunits.
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Mechanisms Governing DDK Regulation of the Initiation of DNA ReplicationThe potent Cdc7-Dbf4 (DDK) kinase inhibitor XL413 has limited activity in many cancer cell lines and discovery of potential new DDK inhibitor scaffoldsThe Dbf4-Cdc7 kinase promotes Mcm2-7 ring opening to allow for single-stranded DNA extrusion and helicase assembly.Structural and mechanistic insights into Mcm2-7 double-hexamer assembly and functionReconstruction of pathway modification induced by nicotinamide using multi-omic network analyses in triple negative breast cancer.Characterization of a Drosophila ortholog of the Cdc7 kinase: a role for Cdc7 in endoreplication independent of Chiffon.Sld3-MCM Interaction Facilitated by Dbf4-Dependent Kinase Defines an Essential Step in Eukaryotic DNA Replication InitiationThe Expression and Prognostic Roles of MCMs in Pancreatic Cancer.A Positive Amplification Mechanism Involving a Kinase and Replication Initiation Factor Helps Assemble the Replication Fork Helicase.Chromosome Duplication in Saccharomyces cerevisiae.Switch on the engine: how the eukaryotic replicative helicase MCM2-7 becomes activated.How the cell cycle impacts chromatin architecture and influences cell fate.Mechanisms and regulation of DNA replication initiation in eukaryotes.Cdk1-mediated phosphorylation of Cdc7 suppresses DNA re-replicationFiring of Replication Origins Frees Dbf4-Cdc7 to Target Eco1 for Destruction.Suppression of targeting of Dbf4-dependent kinase to pre-replicative complex in G0 nuclei.Dbf4 recruitment by forkhead transcription factors defines an upstream rate-limiting step in determining origin firing timing.O-GlcNAc transferase associates with the MCM2-7 complex and its silencing destabilizes MCM-MCM interactions
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P2860
Dbf4 and Cdc7 proteins promote DNA replication through interactions with distinct Mcm2-7 protein subunits.
description
2013 nî lūn-bûn
@nan
2013年の論文
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2013年論文
@yue
2013年論文
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2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
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2013年论文
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2013年论文
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name
Dbf4 and Cdc7 proteins promote ...... tinct Mcm2-7 protein subunits.
@en
type
label
Dbf4 and Cdc7 proteins promote ...... tinct Mcm2-7 protein subunits.
@en
prefLabel
Dbf4 and Cdc7 proteins promote ...... tinct Mcm2-7 protein subunits.
@en
P2093
P2860
P356
P1476
Dbf4 and Cdc7 proteins promote ...... tinct Mcm2-7 protein subunits.
@en
P2093
Evelyin S Suman
Hagen Richter
Karen Stanger
Martina Spranger
Matthew D Ramer
Nicole Bieberstein
P2860
P304
14926-14935
P356
10.1074/JBC.M112.392910
P407
P577
2013-04-02T00:00:00Z