Munc13-1 is a presynaptic phorbol ester receptor that enhances neurotransmitter release.
about
Human munc13 is a diacylglycerol receptor that induces apoptosis and may contribute to renal cell injury in hyperglycemiaDGKι regulates presynaptic release during mGluR-dependent LTDFbxo45, a novel ubiquitin ligase, regulates synaptic activityCharacterization of the Rac-GAP (Rac-GTPase-activating protein) activity of beta2-chimaerin, a 'non-protein kinase C' phorbol ester receptorCast: a novel protein of the cytomatrix at the active zone of synapses that forms a ternary complex with RIM1 and munc13-1The presynaptic active zoneDiacylglycerol kinases in membrane traffickingMolecular mechanisms driving homeostatic plasticity of neurotransmitter releaseDistinct initial SNARE configurations underlying the diversity of exocytosisModular architecture of Munc13/calmodulin complexes: dual regulation by Ca2+ and possible function in short-term synaptic plasticityThe Crystal Structure of a Munc13 C-terminal Module Exhibits a Remarkable Similarity to Vesicle Tethering FactorsMunc13-1 is essential for fusion competence of glutamatergic synaptic vesicles.Phosphorylation of Munc18 by protein kinase C regulates the kinetics of exocytosis.Rab34 and its effector munc13-2 constitute a new pathway modulating protein secretion in the cellular response to hyperglycemiaMolecular cloning and characterization of the human diacylglycerol kinase beta (DGKbeta) gene: alternative splicing generates DGKbeta isotypes with different propertiesDrosophila UNC-13 is essential for synaptic transmissionCAST2: identification and characterization of a protein structurally related to the presynaptic cytomatrix protein CASTInvolvement of protein kinase C in the presynaptic nicotinic modulation of [(3)H]-dopamine release from rat striatal synaptosomesTotal arrest of spontaneous and evoked synaptic transmission but normal synaptogenesis in the absence of Munc13-mediated vesicle primingTransient, phorbol ester-induced DOC2-Munc13 interactions in vivoSCRAPPER-dependent ubiquitination of active zone protein RIM1 regulates synaptic vesicle releaseMunc13-1-mediated vesicle priming contributes to secretory amyloid precursor protein processingAQP2 exocytosis in the renal collecting duct -- involvement of SNARE isoforms and the regulatory role of Munc18bNonconserved Ca(2+)/calmodulin binding sites in Munc13s differentially control synaptic short-term plasticity.CAPS and Munc13 utilize distinct PIP2-linked mechanisms to promote vesicle exocytosisDifferential expression of two novel Munc13 proteins in rat brainDifferent spatiotemporal expression of DOC2 genes in the developing rat brain argues for an additional, nonsynaptic role of DOC2B in early developmentMolecular in situ topology of Aczonin/Piccolo and associated proteins at the mammalian neurotransmitter release siteDefinition of Munc13-homology-domains and characterization of a novel ubiquitously expressed Munc13 isoformInteraction of Doc2 with tctex-1, a light chain of cytoplasmic dynein. Implication in dynein-dependent vesicle transportSize-dependent mechanism of cargo sorting during lysosome-phagosome fusion is controlled by Rab34Presynaptic Calmodulin targets: lessons from structural proteomics.Relating structure and function of inner hair cell ribbon synapses.A molecular toggle after exocytosis sequesters the presynaptic syntaxin1a molecules involved in prior vesicle fusion.Munc18-1 is a dynamically regulated PKC target during short-term enhancement of transmitter releaseA behavioral switch: cGMP and PKC signaling in olfactory neurons reverses odor preference in C. elegans.Synaptic UNC13A protein variant causes increased neurotransmission and dyskinetic movement disorderDynamic modulation of phasic and asynchronous glutamate release in hippocampal synapsesHeterodimerization of Munc13 C2A domain with RIM regulates synaptic vesicle docking and priming.p23/Tmp21 differentially targets the Rac-GAP beta2-chimaerin and protein kinase C via their C1 domains
P2860
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P2860
Munc13-1 is a presynaptic phorbol ester receptor that enhances neurotransmitter release.
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
1998年论文
@zh
1998年论文
@zh-cn
name
Munc13-1 is a presynaptic phorbol ester receptor that enhances neurotransmitter release.
@en
type
label
Munc13-1 is a presynaptic phorbol ester receptor that enhances neurotransmitter release.
@en
prefLabel
Munc13-1 is a presynaptic phorbol ester receptor that enhances neurotransmitter release.
@en
P2093
P1433
P1476
Munc13-1 is a presynaptic phorbol ester receptor that enhances neurotransmitter release.
@en
P2093
P304
P356
10.1016/S0896-6273(00)80520-6
P407
P577
1998-07-01T00:00:00Z