Pituitary corticotroph SOCS-3: novel intracellular regulation of leukemia-inhibitory factor-mediated proopiomelanocortin gene expression and adrenocorticotropin secretion.
about
gp130 cytokine signaling in the pituitary gland: a paradigm for cytokine-neuro-endocrine pathwaysRegulatory network analyses reveal genome-wide potentiation of LIF signaling by glucocorticoids and define an innate cell defense responseArcuate nucleus proopiomelanocortin neurons mediate the acute anorectic actions of leukemia inhibitory factor via gp130.Inhibitory roles for SHP-1 and SOCS-3 following pituitary proopiomelanocortin induction by leukemia inhibitory factorSOCS-3 is tyrosine phosphorylated in response to interleukin-2 and suppresses STAT5 phosphorylation and lymphocyte proliferation.Negative regulation of cytokine signaling by the SOCS proteins.The central role of SOCS-3 in integrating the neuro-immunoendocrine interfaceThe Elongin BC complex interacts with the conserved SOCS-box motif present in members of the SOCS, ras, WD-40 repeat, and ankyrin repeat familiesThe suppression of maternal-fetal leukemia inhibitory factor signal relay pathway by maternal immune activation impairs brain development in mice.Interleukin 31 mediates MAP kinase and STAT1/3 activation in intestinal epithelial cells and its expression is upregulated in inflammatory bowel disease.Autoregulation of pituitary corticotroph SOCS-3 expression: characterization of the murine SOCS-3 promoter.SOCS3, a Major Regulator of Infection and Inflammation.Autocrine IL-6 mediates pituitary tumor senescence.Critical role for STAT3 in murine pituitary adrenocorticotropin hormone leukemia inhibitory factor signaling.Attenuated heme oxygenase-1 responses predispose the elderly to pulmonary nontuberculous mycobacterial infections.Direct regulation of pituitary proopiomelanocortin by STAT3 provides a novel mechanism for immuno-neuroendocrine interfacing.Pravastatin prevents aortic atherosclerosis via modulation of signal transduction and activation of transcription 3 (STAT3) to attenuate interleukin-6 (IL-6) action in ApoE knockout mice.Divergent roles of SHP-2 in ERK activation by leptin receptors.Stat3 beta inhibits gamma-globin gene expression in erythroid cells.
P2860
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P2860
Pituitary corticotroph SOCS-3: novel intracellular regulation of leukemia-inhibitory factor-mediated proopiomelanocortin gene expression and adrenocorticotropin secretion.
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
1998年论文
@zh
1998年论文
@zh-cn
name
Pituitary corticotroph SOCS-3: ...... adrenocorticotropin secretion.
@en
type
label
Pituitary corticotroph SOCS-3: ...... adrenocorticotropin secretion.
@en
prefLabel
Pituitary corticotroph SOCS-3: ...... adrenocorticotropin secretion.
@en
P2093
P356
P1476
Pituitary corticotroph SOCS-3: ...... adrenocorticotropin secretion.
@en
P2093
C Bousquet
C J Auernhammer
V Chesnokova
P304
P356
10.1210/ME.12.7.954
P577
1998-07-01T00:00:00Z