Disruption of vitamin D receptor-retinoid X receptor heterodimer formation following ras transformation of human keratinocytes.
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1,25-Dihydroxyvitamin D3 induced histone profiles guide discovery of VDR action sites1α, 25-Dihydroxyvitamin D regulates hypoxia-inducible factor-1α in untransformed and Harvey-ras transfected breast epithelial cellsMammary epithelial cell transformation is associated with deregulation of the vitamin D pathway.Phosphorylation of Human Retinoid X Receptor α at Serine 260 Impairs Its Subcellular Localization, Receptor Interaction, Nuclear Mobility, and 1α,25-Dihydroxyvitamin D3-dependent DNA Binding in Ras-transformed Keratinocytes.Constitutively active RAS signaling reduces 1,25 dihydroxyvitamin D-mediated gene transcription in intestinal epithelial cells by reducing vitamin D receptor expression.Mechanisms of nuclear vitamin D receptor resistance in Harvey-ras-transfected cells.Phosphorylation of the human retinoid X receptor alpha at serine 260 impairs coactivator(s) recruitment and induces hormone resistance to multiple ligands.The functional consequences of cross-talk between the vitamin D receptor and ERK signaling pathways are cell-specific.Mitogen-activated protein kinase inhibits 1,25-dihydroxyvitamin D3-dependent signal transduction by phosphorylating human retinoid X receptor alpha.Regulation of rat cytochrome P450C24 (CYP24) gene expression. Evidence for functional cooperation of Ras-activated Ets transcription factors with the vitamin D receptor in 1,25-dihydroxyvitamin D(3)-mediated induction.The p38 and JNK pathways cooperate to trans-activate vitamin D receptor via c-Jun/AP-1 and sensitize human breast cancer cells to vitamin D(3)-induced growth inhibition.
P2860
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P2860
Disruption of vitamin D receptor-retinoid X receptor heterodimer formation following ras transformation of human keratinocytes.
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
1998年论文
@zh
1998年论文
@zh-cn
name
Disruption of vitamin D recept ...... mation of human keratinocytes.
@en
type
label
Disruption of vitamin D recept ...... mation of human keratinocytes.
@en
prefLabel
Disruption of vitamin D recept ...... mation of human keratinocytes.
@en
P2093
P2860
P356
P1476
Disruption of vitamin D recept ...... mation of human keratinocytes.
@en
P2093
P2860
P304
17573-17578
P356
10.1074/JBC.273.28.17573
P407
P577
1998-07-01T00:00:00Z