The virion host shutoff protein of herpes simplex virus type 1 has RNA degradation activity in primary neurons.
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The herpes simplex virus type 1 vhs-UL41 gene secures viral replication by temporarily evading apoptotic cellular response to infection: Vhs-UL41 activity might require interactions with elements of cellular mRNA degradation machinery.The virion host shut-off (vhs) protein blocks a TLR-independent pathway of herpes simplex virus type 1 recognition in human and mouse dendritic cells.Frequent release of low amounts of herpes simplex virus from neurons: results of a mathematical model.Phosphorylation of the VP16 transcriptional activator protein during herpes simplex virus infection and mutational analysis of putative phosphorylation sites.Selective ablation of virion host shutoff protein RNase activity attenuates herpes simplex virus 2 in mice.Deletion of the Virion Host Shut-off Gene Enhances Neuronal-Selective Transgene Expression from an HSV Vector Lacking Functional IE Genes.
P2860
The virion host shutoff protein of herpes simplex virus type 1 has RNA degradation activity in primary neurons.
description
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name
The virion host shutoff protei ...... n activity in primary neurons.
@en
type
label
The virion host shutoff protei ...... n activity in primary neurons.
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prefLabel
The virion host shutoff protei ...... n activity in primary neurons.
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P2093
P2860
P1433
P1476
The virion host shutoff protei ...... n activity in primary neurons.
@en
P2093
David A Leib
Stephanie S Strand
Tambryn K Vanheyningen
P2860
P304
P356
10.1128/JVI.78.15.8400-8403.2004
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P577
2004-08-01T00:00:00Z