Conformationally defined retinoic acid analogues. 4. Potential new agents for acute promyelocytic and juvenile myelomonocytic leukemias.
about
The retinoid X receptors and their ligandsDefining the Communication between Agonist and Coactivator Binding in the Retinoid X Receptor Ligand Binding DomainMethyl-substituted conformationally constrained rexinoid agonists for the retinoid X receptors demonstrate improved efficacy for cancer therapy and preventionMethyl Substitution of a Rexinoid Agonist Improves Potency and Reveals Site of Lipid ToxicityAdvances in drug design with RXR modulatorsRetinoid X Receptor Agonists Upregulate Genes Responsible for the Biosynthesis of All-Trans-Retinoic Acid in Human EpidermisMyelodysplasia and myeloproliferative disorders in childhood: an update.A pilot, first-in-human, pharmacokinetic study of 9cUAB30 in healthy volunteers.Effects on gene expression in rat liver after administration of RXR agonists: UAB30, 4-methyl-UAB30, and Targretin (Bexarotene).The low-toxicity 9-cis UAB30 novel retinoid down-regulates the DNA methyltransferases and has anti-telomerase activity in human breast cancer cellsThe Novel Retinoid, 9cUAB30, Inhibits Telomerase and Induces Apoptosis in HL60 Cells.Conformationally Defined Rexinoids and Their Efficacy in the Prevention of Mammary CancersPrevention of KLF4-mediated tumor initiation and malignant transformation by UAB30 rexinoid.Murine oncogenicity and pharmacokinetics studies of 9-cis-UAB30, an RXR agonist, for breast cancer chemoprevention.
P2860
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P2860
Conformationally defined retinoic acid analogues. 4. Potential new agents for acute promyelocytic and juvenile myelomonocytic leukemias.
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
1998年论文
@zh
1998年论文
@zh-cn
name
Conformationally defined retin ...... nile myelomonocytic leukemias.
@en
type
label
Conformationally defined retin ...... nile myelomonocytic leukemias.
@en
prefLabel
Conformationally defined retin ...... nile myelomonocytic leukemias.
@en
P2093
P356
P1476
Conformationally defined retin ...... nile myelomonocytic leukemias.
@en
P2093
Breitman TR
Brouillette WJ
Emanuel PD
Simpson-Herren L
P304
P356
10.1021/JM970635H
P407
P577
1998-05-01T00:00:00Z