Dose- and time-dependent effect of high glucose concentration on viability of notochordal cells and expression of matrix degrading and fibrotic enzymes
about
Collagen-derived N-acetylated proline-glycine-proline upregulates the expression of pro-inflammatory cytokines and extracellular matrix proteases in nucleus pulposus cells via the NF-κB and MAPK signaling pathways.Activation of intervertebral disc cells by co-culture with notochordal cells, conditioned medium and hypoxia.Effect of coculturing canine notochordal, nucleus pulposus and mesenchymal stromal cells for intervertebral disc regeneration.ROS: Crucial Intermediators in the Pathogenesis of Intervertebral Disc Degeneration.Responses and adaptations of intervertebral disc cells to microenvironmental stress: a possible central role of autophagy in the adaptive mechanism.Alterations of tendons in diabetes mellitus: what are the current findings?Effect of RNA Interference-Mediated Suppression of p75 on the Viability of Rat Notochordal Cells.Effect of high glucose on stress-induced senescence of nucleus pulposus cells of adult rats.Accelerated premature stress-induced senescence of young annulus fibrosus cells of rats by high glucose-induced oxidative stressRat Notochordal Cells Undergo Premature Stress-Induced Senescence by High Glucose.High glucose accelerates autophagy in adult rat intervertebral disc cells.The Regenerative Potential of Notochordal Cells in a Nucleus Pulposus Explant.Comment on Park et al.: High glucose-induced oxidative stress promotes autophagy through mitochondrial damage in rat notochordal cells.High glucose-induced oxidative stress promotes autophagy through mitochondrial damage in rat notochordal cells.Whether reactive oxygen species plays a critical role in intrinsic (mitochondrial) pathway-mediated apoptosis in notochordal cells under high glucose concentrations?Resveratrol attenuates high glucose-induced nucleus pulposus cell apoptosis and senescence through activating the ROS-mediated PI3K/Akt pathway.Transcriptome and alternative splicing analysis of nucleus pulposus cells in response to high oxygen tension: Involvement of high oxygen tension in the pathogenesis of intervertebral disc degeneration.Cyclic mechanical tension reinforces DNA damage and activates the p53-p21-Rb pathway to induce premature senescence of nucleus pulposus cells.
P2860
Q33783964-D0D0B522-8747-48E9-B871-17E48B9C6EFAQ34969332-8ECE46A1-526B-41E1-94EA-FF1806A27632Q35410066-D733F5D9-9E58-4604-A5DC-C2F9BF4A396CQ37723678-D944832E-4812-42D8-919A-65DCAD593C8DQ38226918-66979473-F5AA-447C-82A9-18F8D87C4E04Q38461078-5F0410F5-DFAB-4BC4-B430-6B48188F38C4Q39254214-7C3D56CE-A517-448C-904C-E904A2A868B9Q39825642-DF738B51-606B-44FC-ADFB-0747BD35F7B0Q40027991-9AE96013-0AA7-4300-A5A6-7C7E78F70E0FQ42146019-E38451C2-C4FC-4603-AD53-0F8DC672C3D6Q42146300-4D880F46-9AD4-4FE4-AFF7-502D8F3F9008Q42290831-B694205A-519C-4ECC-8C15-EFE0724E11C1Q42429468-42BAE283-8155-4733-A4E1-2E0EBEE6C1F3Q42861656-BD824B48-BED1-42A5-B4F4-DBDD0770270BQ43067280-F1A4FC78-1F25-4754-BE4D-44DBE3B3A664Q49606831-EE1138AC-536A-4033-8698-A2A34301FE97Q52670066-1F6B8532-29DF-4549-9ACA-39B72CC848D2Q52670101-F5885570-9838-4A4F-8089-244A52779512
P2860
Dose- and time-dependent effect of high glucose concentration on viability of notochordal cells and expression of matrix degrading and fibrotic enzymes
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
Dose- and time-dependent effec ...... degrading and fibrotic enzymes
@en
type
label
Dose- and time-dependent effec ...... degrading and fibrotic enzymes
@en
prefLabel
Dose- and time-dependent effec ...... degrading and fibrotic enzymes
@en
P2860
P1476
Dose- and time-dependent effec ...... degrading and fibrotic enzymes
@en
P2093
Eun-Young Park
Jong-Beon Park
P2860
P2888
P304
P356
10.1007/S00264-013-1836-2
P577
2013-03-16T00:00:00Z
P6179
1010564784