PD98059 is an equipotent antagonist of the aryl hydrocarbon receptor and inhibitor of mitogen-activated protein kinase kinase.
about
Antiproliferative and apoptotic effects of selective phenolic acids on T47D human breast cancer cells: potential mechanisms of actionThe aryl hydrocarbon receptor mediates degradation of estrogen receptor alpha through activation of proteasomesFacilitation of AMPA receptor synaptic delivery as a molecular mechanism for cognitive enhancementStructural and functional analysis of phosphorylation-specific binders of the kinase ERK from designed ankyrin repeat protein librariesDietary flavonols quercetin and kaempferol are ligands of the aryl hydrocarbon receptor that affect CYP1A1 transcription differentiallyThe Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivityAntagonism of aryl hydrocarbon receptor signaling by 6,2',4'-trimethoxyflavoneThe Ah receptor recruits IKKα to its target binding motifs to phosphorylate serine-10 in histone H3 required for transcriptional activation.Insulin-sensitizing and anti-proliferative effects of Argania spinosa seed extracts.2,3,7,8-Tetrachlorodibenzo-p-dioxin-induced MUC5AC expression: aryl hydrocarbon receptor-independent/EGFR/ERK/p38-dependent SP1-based transcriptionActivation of the aryl hydrocarbon receptor by the widely used Src family kinase inhibitor 4-amino-5-(4-chlorophenyl)-7-(dimethylethyl)pyrazolo[3,4-d]pyrimidine (PP2).A constitutive active MAPK/ERK pathway due to BRAFV600E positively regulates AHR pathway in PTC.Testosterone-dependent interaction between androgen receptor and aryl hydrocarbon receptor induces liver receptor homolog 1 expression in rat granulosa cells.The aryl hydrocarbon receptor cross-talks with multiple signal transduction pathways.In search for geroprotectors: in silico screening and in vitro validation of signalome-level mimetics of young healthy state.Beta-naphthoflavone (DB06732) mediates estrogen receptor-positive breast cancer cell cycle arrest through AhR-dependent regulation of PI3K/AKT and MAPK/ERK signaling.Autocrine and paracrine STIP1 signaling promote osteolytic bone metastasis in renal cell carcinoma.GW5074 and PP2 kinase inhibitors implicate nontraditional c-Raf and Lyn function as drivers of retinoic acid-induced maturation.Chenodeoxycholic acid increases the induction of CYP1A1 in HepG2 and H4IIE cells.AhR and SHP regulate phosphatidylcholine and S-adenosylmethionine levels in the one-carbon cycle.PINOID positively regulates auxin efflux in Arabidopsis root hair cells and tobacco cells.Commentary: Usage of Mitogen-Activated Protein Kinase Small Molecule Inhibitors: More Than Just Inhibition!
P2860
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P2860
PD98059 is an equipotent antagonist of the aryl hydrocarbon receptor and inhibitor of mitogen-activated protein kinase kinase.
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年学术文章
@wuu
1998年学术文章
@zh-cn
1998年学术文章
@zh-hans
1998年学术文章
@zh-my
1998年学术文章
@zh-sg
1998年學術文章
@yue
1998年學術文章
@zh
1998年學術文章
@zh-hant
name
PD98059 is an equipotent antag ...... tivated protein kinase kinase.
@en
type
label
PD98059 is an equipotent antag ...... tivated protein kinase kinase.
@en
prefLabel
PD98059 is an equipotent antag ...... tivated protein kinase kinase.
@en
P2093
P1476
PD98059 is an equipotent antag ...... tivated protein kinase kinase.
@en
P2093
P304
P577
1998-03-01T00:00:00Z