Strategic internal covalent cross-linking of TNF produces a stable TNF trimer with improved TNFR2 signaling.
about
Exogenous TNFR2 activation protects from acute GvHD via host T reg cell expansion.Novel strategies to mimic transmembrane tumor necrosis factor-dependent activation of tumor necrosis factor receptor 2.A trimeric structural fusion of an antagonistic tumor necrosis factor-α mutant enhances molecular stability and enables facile modification.Creation of mouse TNFR2-selective agonistic TNF mutants using a phage display technique.Structural principles of tumor necrosis factor superfamily signaling.Modulation of Regulatory T Cell Activity by TNF Receptor Type II-Targeting Pharmacological Agents.
P2860
Strategic internal covalent cross-linking of TNF produces a stable TNF trimer with improved TNFR2 signaling.
description
2015 nî lūn-bûn
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2015年の論文
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2015年学术文章
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2015年学术文章
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2015年学术文章
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2015年学术文章
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2015年学术文章
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2015年學術文章
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2015年學術文章
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2015年學術文章
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name
Strategic internal covalent cr ...... with improved TNFR2 signaling.
@en
type
label
Strategic internal covalent cr ...... with improved TNFR2 signaling.
@en
prefLabel
Strategic internal covalent cr ...... with improved TNFR2 signaling.
@en
P2093
P2860
P1476
Strategic internal covalent cr ...... with improved TNFR2 signaling.
@en
P2093
Denise L Faustman
John Butterworth
Willem Kuhtreiber
Yoshiaki Okubo
Éva S Vanamee
P2860
P2888
P356
10.1186/S40591-015-0044-4
P577
2015-08-12T00:00:00Z
P5875
P6179
1037067284