The C-terminal region of the motor protein MCAK controls its structure and activity through a conformational switch.
about
The far C-terminus of MCAK regulates its conformation and spindle pole focusing.Coordination of Synthesis and Assembly of a Modular Membrane-Associated [NiFe]-Hydrogenase Is Determined by Cleavage of the C-Terminal Peptide.Molecular architecture of the Dam1 complex-microtubule interaction.Insight into microtubule disassembly by kinesin-13s from the structure of Kif2C bound to tubulin.NuSAP modulates the dynamics of kinetochore microtubules by attenuating MCAK depolymerisation activity.GTSE1 tunes microtubule stability for chromosome alignment and segregation by inhibiting the microtubule depolymerase MCAK.Control of microtubule organization and dynamics: two ends in the limelight.Molecular insight into the regulation and function of MCAK.The family-specific α4-helix of the kinesin-13, MCAK, is critical to microtubule end recognition.A Cdk1 phosphomimic mutant of MCAK impairs microtubule end recognition.A small-molecule activator of kinesin-1 drives remodeling of the microtubule network.Microtubule end tethering of a processive kinesin-8 motor Kif18b is required for spindle positioning.Insights into Kinesin-1 Activation from the Crystal Structure of KLC2 Bound to JIP3
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P2860
The C-terminal region of the motor protein MCAK controls its structure and activity through a conformational switch.
description
2015 nî lūn-bûn
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2015年の論文
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2015年学术文章
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2015年学术文章
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name
The C-terminal region of the m ...... rough a conformational switch.
@en
type
label
The C-terminal region of the m ...... rough a conformational switch.
@en
prefLabel
The C-terminal region of the m ...... rough a conformational switch.
@en
P2860
P356
P1433
P1476
The C-terminal region of the m ...... hrough a conformational switch
@en
P2093
Bethany Harker
Sandeep K Talapatra
P2860
P356
10.7554/ELIFE.06421
P407
P577
2015-04-27T00:00:00Z