One-step generation of complete gene knockout mice and monkeys by CRISPR/Cas9-mediated gene editing with multiple sgRNAs.
about
CRISPR Editing in Biological and Biomedical Investigation.Generation of knock-in cynomolgus monkey via CRISPR/Cas9 editing.SaCas9 Requires 5'-NNGRRT-3' PAM for Sufficient Cleavage and Possesses Higher Cleavage Activity than SpCas9 or FnCpf1 in Human Cells.Of Men and Mice: Modeling the Fragile X Syndrome.Efficient generation of mouse models of human diseases via ABE- and BE-mediated base editing.Application of the CRISPR/Cas9 System to Drug Resistance in Breast Cancer.Comparative analysis of single-stranded DNA donors to generate conditional null mouse alleles.Covalent linkage of the DNA repair template to the CRISPR-Cas9 nuclease enhances homology-directed repair.CRISPR/Cascade 9-Mediated Genome Editing-Challenges and Opportunities
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P2860
One-step generation of complete gene knockout mice and monkeys by CRISPR/Cas9-mediated gene editing with multiple sgRNAs.
description
2017 nî lūn-bûn
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2017年の論文
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2017年学术文章
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2017年学术文章
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2017年学术文章
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2017年学术文章
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2017年学术文章
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2017年學術文章
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2017年學術文章
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2017年學術文章
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name
One-step generation of complet ...... editing with multiple sgRNAs.
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type
label
One-step generation of complet ...... editing with multiple sgRNAs.
@en
prefLabel
One-step generation of complet ...... editing with multiple sgRNAs.
@en
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P2860
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One-step generation of complet ...... editing with multiple sgRNAs.
@en
P2093
Bang-An Wang
Changyang Zhou
Chen-Chen Zhang
Cheng Tang
Guo-Liang Xu
Jinsong Li
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10.1038/CR.2017.81
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2017-06-06T00:00:00Z
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1085881959