The G222D mutation in elongation factor Tu inhibits the codon-induced conformational changes leading to GTPase activation on the ribosome
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The Crystal Structure of the Ribosome Bound to EF-Tu and Aminoacyl-tRNAStructural insights into cognate versus near-cognate discrimination during decoding.Reorganization of an intersubunit bridge induced by disparate 16S ribosomal ambiguity mutations mimics an EF-Tu-bound stateStructure of the mammalian ribosomal pre-termination complex associated with eRF1*eRF3*GDPNPrRNA suppressor of a eukaryotic translation initiation factor 5B/initiation factor 2 mutant reveals a binding site for translational GTPases on the small ribosomal subunit.Evolutionary optimization of speed and accuracy of decoding on the ribosomeMissense suppressor mutations in 16S rRNA reveal the importance of helices h8 and h14 in aminoacyl-tRNA selection.Codon-dependent tRNA fluctuations monitored with fluorescence polarization.Interaction strengths between the ribosome and tRNA at various steps of translocation.Two proofreading steps amplify the accuracy of genetic code translationThe unique tuf2 gene from the kirromycin producer Streptomyces ramocissimus encodes a minor and kirromycin-sensitive elongation factor Tu.Distortion of tRNA upon near-cognate codon recognition on the ribosome.Complete kinetic mechanism of elongation factor Tu-dependent binding of aminoacyl-tRNA to the A site of the E. coli ribosomeStructure of a novel antibacterial toxin that exploits elongation factor Tu to cleave specific transfer RNAs.
P2860
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P2860
The G222D mutation in elongation factor Tu inhibits the codon-induced conformational changes leading to GTPase activation on the ribosome
description
1996 nî lūn-bûn
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1996年の論文
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1996年学术文章
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1996年学术文章
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1996年学术文章
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name
The G222D mutation in elongati ...... ase activation on the ribosome
@en
type
label
The G222D mutation in elongati ...... ase activation on the ribosome
@en
prefLabel
The G222D mutation in elongati ...... ase activation on the ribosome
@en
P2093
P2860
P1433
P1476
The G222D mutation in elongati ...... ase activation on the ribosome
@en
P2093
Vorstenbosch E
Wintermeyer W
P2860
P304
P407
P577
1996-12-01T00:00:00Z