Ligation of the T cell co-stimulatory receptor CD28 activates the serine-threonine protein kinase protein kinase B.
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Induction of glucose metabolism in stimulated T lymphocytes is regulated by mitogen-activated protein kinase signalingRegulation of apoptosis by the Ft1 protein, a new modulator of protein kinase B/AktCTLA-4 and PD-1 receptors inhibit T-cell activation by distinct mechanismsTCR Signaling in T Cell MemoryTargeting CD8 T-Cell Metabolism in TransplantationUnifying concepts in CD28, ICOS and CTLA4 co-receptor signallingComplex formation and cooperation of protein kinase C theta and Akt1/protein kinase B alpha in the NF-kappa B transactivation cascade in Jurkat T cellsThe costimulation-regulated duration of PKB activation controls T cell longevityAn important role of CDK inhibitor p18(INK4c) in modulating antigen receptor-mediated T cell proliferationEphrinB1 is essential in T-cell-T-cell co-operation during T-cell activationModulation of cell signaling networks after CTLA4 blockade in patients with metastatic melanomaT cell Ig and mucin domain-1-mediated T cell activation requires recruitment and activation of phosphoinositide 3-kinaseAkt provides the CD28 costimulatory signal for up-regulation of IL-2 and IFN-gamma but not TH2 cytokines.The B7/CD28/CTLA4 T-cell activation pathway. Implications for inflammatory lung disease.Insulin-like growth factor-I regulation of immune function: a potential therapeutic target in autoimmune diseases?An enigmatic tail of CD28 signaling.B7-H4 Treatment of T Cells Inhibits ERK, JNK, p38, and AKT ActivationActivation and inhibition of lymphocytes by costimulation.4-1BB signaling activates the t cell factor 1 effector/β-catenin pathway with delayed kinetics via ERK signaling and delayed PI3K/AKT activation to promote the proliferation of CD8+ T CellsOver-expressing Akt in T cells to resist tumor immunosuppression and increase anti-tumor activityExpression of PD-1 Molecule on Regulatory T Lymphocytes in Patients with Insulin-Dependent Diabetes Mellitus.Lymphocyte calcium signaling from membrane to nucleus.Protein kinase B regulates T lymphocyte survival, nuclear factor kappaB activation, and Bcl-X(L) levels in vivoCD28-dependent activation of protein kinase B/Akt blocks Fas-mediated apoptosis by preventing death-inducing signaling complex assembly.Feeding our immune system: impact on metabolism.mTOR at the crossroads of T cell proliferation and tolerance.Glucose metabolism in lymphocytes is a regulated process with significant effects on immune cell function and survival.Targeted knock-in mice expressing mutations of CD28 reveal an essential pathway for costimulationSuppression of activation and costimulatory signaling in splenic CD4+ T cells after trauma-hemorrhage reduces T-cell function: a mechanism of post-traumatic immune suppression.CD28 delivers a unique signal leading to the selective recruitment of RelA and p52 NF-kappaB subunits on IL-8 and Bcl-xL gene promoters.Chimeric antigen receptors combining 4-1BB and CD28 signaling domains augment PI3kinase/AKT/Bcl-XL activation and CD8+ T cell-mediated tumor eradication.Inhibition of T-cell activation by PIK3IP1.Cytokine-induced apoptosis in epithelial HT-29 cells is independent of nitric oxide formation. Evidence for an interleukin-13-driven phosphatidylinositol 3-kinase-dependent survival mechanism.A cellular platform for the evaluation of immune checkpoint molecules.Cell cycle progression following naive T cell activation is independent of Jak3/common gamma-chain cytokine signals.Vav1 couples T cell receptor to serum response factor-dependent transcription via a MEK-dependent pathway.Enhanced activity of Akt in Teff cells from children with lupus nephritis is associated with reduced induction of tumor necrosis factor receptor-associated factor 6 and increased OX40 expression.Wortmannin inhibits translation of tumor necrosis factor-alpha in superantigen-activated T cells.Disparate effects of phorbol esters, CD3 and the costimulatory receptors CD2 and CD28 on RANTES secretion by human T lymphocytes
P2860
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P2860
Ligation of the T cell co-stimulatory receptor CD28 activates the serine-threonine protein kinase protein kinase B.
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年学术文章
@wuu
1997年学术文章
@zh-cn
1997年学术文章
@zh-hans
1997年学术文章
@zh-my
1997年学术文章
@zh-sg
1997年學術文章
@yue
1997年學術文章
@zh
1997年學術文章
@zh-hant
name
Ligation of the T cell co-stim ...... otein kinase protein kinase B.
@en
type
label
Ligation of the T cell co-stim ...... otein kinase protein kinase B.
@en
prefLabel
Ligation of the T cell co-stim ...... otein kinase protein kinase B.
@en
P2093
P2860
P356
P1476
Ligation of the T cell co-stim ...... rotein kinase protein kinase B
@en
P2093
P2860
P304
P356
10.1002/EJI.1830271006
P407
P577
1997-10-01T00:00:00Z